The TNF receptor superfamily in co-stimulating and co-inhibitory responses
Cytokines related to tumor necrosis factor (TNF) provide a communication network essential
for coordinating multiple cell types into an effective host defense system against pathogens …
for coordinating multiple cell types into an effective host defense system against pathogens …
Mesenchymal stem cells: a new strategy for immunosuppression?
In vitro-generated mesenchymal stem cells (MSCs) initially attracted interest for their ability
to undergo differentiation toward cells of different lineages. More recently, a major …
to undergo differentiation toward cells of different lineages. More recently, a major …
Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
Mesenchymal stem cells (MSCs) can become potently immunosuppressive through
unknown mechanisms. We found that the immunosuppressive function of MSCs is elicited …
unknown mechanisms. We found that the immunosuppressive function of MSCs is elicited …
Effects of sex and aging on the immune cell landscape as assessed by single-cell transcriptomic analysis
Z Huang, B Chen, X Liu, H Li, L **e… - Proceedings of the …, 2021 - National Acad Sciences
Sex and aging influence the human immune system, resulting in disparate responses to
infection, autoimmunity, and cancer. However, the impact of sex and aging on the immune …
infection, autoimmunity, and cancer. However, the impact of sex and aging on the immune …
The TNF–TNFR family of co-signal molecules
T So, N Ishii - Co-signal Molecules in T Cell Activation: Immune …, 2019 - Springer
Costimulatory signals initiated by the interaction between the tumor necrosis factor (TNF)
ligand and cognate TNF receptor (TNFR) superfamilies promote clonal expansion …
ligand and cognate TNF receptor (TNFR) superfamilies promote clonal expansion …
The signaling networks of the herpesvirus entry mediator (TNFRSF14) in immune regulation
MW Steinberg, TC Cheung, CF Ware - Immunological reviews, 2011 - Wiley Online Library
The tumor necrosis factor (TNF) receptor superfamily member herpesvirus entry mediator
(HVEM)(TNFRSF14) regulates T‐cell immune responses by activating both inflammatory …
(HVEM)(TNFRSF14) regulates T‐cell immune responses by activating both inflammatory …
Timing and tuning of CD27–CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology
MA Nolte, RW Van Olffen… - Immunological …, 2009 - Wiley Online Library
After binding its natural ligand cluster of differentiation 70 (CD70), CD27, a tumor necrosis
factor receptor (TNFR)‐associated factor‐binding member of the TNFR family, regulates …
factor receptor (TNFR)‐associated factor‐binding member of the TNFR family, regulates …
Ectopic lymphoid tissues and local immunity
Ectopic or tertiary lymphoid tissues develop at sites of inflammation or infection in peripheral,
non-lymphoid organs. These tissues are architecturally similar to conventional secondary …
non-lymphoid organs. These tissues are architecturally similar to conventional secondary …
Cell surface signaling molecules in the control of immune responses: a tide model
Y Zhu, S Yao, L Chen - Immunity, 2011 - cell.com
A large numbers of cell surface signaling molecules (CSSMs) have been molecularly
identified and functionally characterized in recent years and, via these studies, our …
identified and functionally characterized in recent years and, via these studies, our …
Slow down and survive: Enigmatic immunoregulation by BTLA and HVEM
TL Murphy, KM Murphy - Annual review of immunology, 2009 - annualreviews.org
B and T lymphocyte associated (BTLA) is an Ig domain superfamily protein with cytoplasmic
immunoreceptor tyrosine-based inhibitory motifs. Its ligand, herpesvirus entry mediator …
immunoreceptor tyrosine-based inhibitory motifs. Its ligand, herpesvirus entry mediator …