Detection and analysis of chiral molecules as disease biomarkers

Y Liu, Z Wu, DW Armstrong, H Wolosker… - Nature Reviews …, 2023 - nature.com
The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …

Quality assurance procedures for mass spectrometry untargeted metabolomics. a review

D Dudzik, C Barbas-Bernardos, A García… - … of pharmaceutical and …, 2018 - Elsevier
Untargeted metabolomics, as a global approach, has already proven its great potential and
capabilities for the investigation of health and disease, as well as the wide applicability for …

Individual variability in human blood metabolites identifies age-related differences

R Chaleckis, I Murakami, J Takada… - Proceedings of the …, 2016 - National Acad Sciences
Metabolites present in human blood document individual physiological states influenced by
genetic, epigenetic, and lifestyle factors. Using high-resolution liquid chromatography-mass …

Metabolomics: small molecules that matter more

BC Muthubharathi, T Gowripriya, K Balamurugan - Molecular omics, 2021 - pubs.rsc.org
Metabolomics, an analytical study with high-throughput profiling, helps to understand
interactions within a biological system. Small molecules, called metabolites or metabolomes …

Integrated multi‐omics approaches to understand microbiome assembly in Jiuqu, a mixed‐culture starter

J Kang, Y Xue, X Chen, BZ Han - Comprehensive Reviews in …, 2022 - Wiley Online Library
The use of Jiuqu as a saccharifying and fermenting starter in the production of fermented
foods is a very old biotechnological process that can be traced back to ancient times. Jiuqu …

Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests

FA Castelli, G Rosati, C Moguet, C Fuentes… - Analytical and …, 2022 - Springer
Metabolomics refers to the large-scale detection, quantification, and analysis of small
molecules (metabolites) in biological media. Although metabolomics, alone or combined …

Lactate shuttles in neuroenergetics—homeostasis, allostasis and beyond

S Mason - Frontiers in neuroscience, 2017 - frontiersin.org
Understanding brain energy metabolism—neuroenergetics—is becoming increasingly
important as it can be identified repeatedly as the source of neurological perturbations …

Metabolomics: definitions and significance in systems biology

A Klassen, AT Faccio, GAB Canuto… - … : from fundamentals to …, 2017 - Springer
Nowadays, there is a growing interest in deeply understanding biological mechanisms not
only at the molecular level (biological components) but also the effects of an ongoing …

[HTML][HTML] Biomarker discovery in human prostate cancer: an update in metabolomics studies

AR Lima, M de Lourdes Bastos, M Carvalho… - Translational …, 2016 - Elsevier
Prostate cancer (PCa) is the most frequently diagnosed cancer and the second leading
cause of cancer death among men in Western countries. Current screening techniques are …

Potentially Bioactive Metabolites from Pineapple Waste Extracts and Their Antioxidant and α-Glucosidase Inhibitory Activities by 1H NMR

A Azizan, AX Lee, NA Abdul Hamid, M Maulidiani… - Foods, 2020 - mdpi.com
Pineapple (Ananas comosus) waste is a promising source of metabolites for therapeutics,
functional foods, and cosmeceutical applications. This study strives to characterize the …