Most bacteria have multiple peptidoglycan hydrolases capable of cleaving covalent bonds in
peptidoglycan sacculi or its fragments. An overview of the different classes of peptidoglycan …

The bactericidal, cell membrane–targeting lipopeptide antibiotic daptomycin (DAP) is an
important agent in treating invasive Staphylococcus aureus infections. However, there have …

SCC mec is a large mobile genetic element that includes the mecA gene and confers
resistance to β-lactam antibiotics in methicillin-resistant Staphylococcus aureus (MRSA) …

The spread of multidrug-resistant Staphylococcus aureus (MRSA) strains in the clinical
environment has begun to pose serious limits to treatment options. Yet virtually nothing is …

RNAIII is the intracellular effector of the quorum-sensing system in Staphylococcus aureus. It
is one of the largest regulatory RNAs (514 nucleotides long) that are known to control the …

Daptomycin (DAP) is a cyclic lipopeptide with in vitro activity against a variety of Gram‐
positive pathogens, including multidrug‐resistant organisms. Since its introduction into …

Daptomycin is a lipopeptide antibiotic with potent activity against gram-positive bacteria.
Complete-genome comparisons of laboratory-derived Staphylococcus aureus with …

Antimicrobial resistance in Staphylococcus aureus is a major public health threat,
compounded by emergence of strains with resistance to vancomycin and daptomycin, both …

Genes | Free Full-Text | Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms
Next Article in Journal Genome-Wide Identification, Primary Functional Characterization of the …

Lipopeptides are natural product antibiotics that consist of a peptide core with a lipid tail with
a diverse array of target organisms and mechanisms of action. Daptomycin (DAP) is an …