γδ T cells in tissue physiology and surveillance
JC Ribot, N Lopes, B Silva-Santos - Nature Reviews Immunology, 2021 - nature.com
Abstract γδ T cells are a unique T cell subpopulation that are rare in secondary lymphoid
organs but enriched in many peripheral tissues, such as the skin, intestines and lungs. By …
organs but enriched in many peripheral tissues, such as the skin, intestines and lungs. By …
Cancer immunoediting: from immunosurveillance to tumor escape
GP Dunn, AT Bruce, H Ikeda, LJ Old… - Nature immunology, 2002 - nature.com
The concept that the immune system can recognize and destroy nascent transformed cells
was originally embodied in the cancer immunosurveillance hypothesis of Burnet and …
was originally embodied in the cancer immunosurveillance hypothesis of Burnet and …
CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract
JM Brenchley, TW Schacker, LE Ruff… - The Journal of …, 2004 - rupress.org
The mechanisms underlying CD4+ T cell depletion in human immunodeficiency virus (HIV)
infection are not well understood. Comparative studies of lymphoid tissues, where the vast …
infection are not well understood. Comparative studies of lymphoid tissues, where the vast …
γδ T cells: functional plasticity and heterogeneity
SR Carding, PJ Egan - Nature reviews immunology, 2002 - nature.com
Abstract γδ T cells remain an enigma. They are capable of generating more unique antigen
receptors than αβ T cells and B cells combined, yet their repertoire of antigen receptors is …
receptors than αβ T cells and B cells combined, yet their repertoire of antigen receptors is …
Professional antigen-presentation function by human γδ T cells
M Brandes, K Willimann, B Moser - Science, 2005 - science.org
Human γδ T cells are considered to play a vital role in protective immunity through cytokine
secretion and cytotoxic activity. We report that cells expressing the Vγ2Vδ2+–T cell receptor …
secretion and cytotoxic activity. We report that cells expressing the Vγ2Vδ2+–T cell receptor …
Genomic analysis of the host response to hepatitis B virus infection
S Wieland, R Thimme, RH Purcell… - Proceedings of the …, 2004 - National Acad Sciences
Previous studies in hepatitis B virus (HBV)-infected humans and chimpanzees suggest that
control of HBV infection involves the cells, effector functions, and molecular mediators of the …
control of HBV infection involves the cells, effector functions, and molecular mediators of the …
Epithelia use butyrophilin-like molecules to shape organ-specific γδ T cell compartments
RDM Barros, NA Roberts, RJ Dart, P Vantourout… - Cell, 2016 - cell.com
Many body surfaces harbor organ-specific γδ T cell compartments that contribute to tissue
integrity. Thus, murine dendritic epidermal T cells (DETCs) uniquely expressing T cell …
integrity. Thus, murine dendritic epidermal T cells (DETCs) uniquely expressing T cell …
T cell-mediated immunity to malaria
Immunity to malaria has been linked to the availability and function of helper CD4+ T cells,
cytotoxic CD8+ T cells and γδ T cells that can respond to both the asymptomatic liver stage …
cytotoxic CD8+ T cells and γδ T cells that can respond to both the asymptomatic liver stage …
A role for skin γδ T cells in wound repair
J Jameson, K Ugarte, N Chen, P Yachi, E Fuchs… - Science, 2002 - science.org
γδ T cell receptor–bearing dendritic epidermal T cells (DETCs) found in murine skin
recognize antigen expressed by damaged or stressed keratinocytes. Activated DETCs …
recognize antigen expressed by damaged or stressed keratinocytes. Activated DETCs …
Stepwise development of MAIT cells in mouse and human
Mucosal-associated invariant T (MAIT) cells display two evolutionarily conserved features:
an invariant T cell receptor (TCR) α (iTCRα) chain and restriction by the nonpolymorphic …
an invariant T cell receptor (TCR) α (iTCRα) chain and restriction by the nonpolymorphic …