Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Detection and beyond: Challenges and advances in aptamer-based biosensors

H Yoo, H Jo, SS Oh - Materials Advances, 2020 - pubs.rsc.org
Beyond traditional needs of biosensors such as high sensitivity and selectivity for analyte
detection, newly emerging requirements including a real-time detection ability and in-field …

[HTML][HTML] Recent advances in quantum dots-based biosensors for antibiotics detection

R Ding, Y Chen, Q Wang, Z Wu, X Zhang, B Li… - Journal of …, 2022 - Elsevier
Antibiotics are a category of chemical compounds used to treat bacterial infections and are
widely applied in cultivation, animal husbandry, aquaculture, and pharmacy. Currently …

Nanoparticle‐based bioaffinity assays: from the research laboratory to the market

Z Farka, JC Brandmeier, MJ Mickert… - Advanced …, 2024 - Wiley Online Library
Advances in the development of new biorecognition elements, nanoparticle‐based labels as
well as instrumentation have inspired the design of new bioaffinity assays. This review …

Rapid and sensitive exosome detection with CRISPR/Cas12a

X Zhao, W Zhang, X Qiu, Q Mei, Y Luo, W Fu - Analytical and bioanalytical …, 2020 - Springer
Numerous studies have shown that exosomes are closely related to the pathogenesis of
various diseases, especially cancers. Therefore, a rapid and sensitive method for exosome …

Design and prediction of aptamers assisted by in silico methods

SJ Lee, J Cho, BH Lee, D Hwang, JW Park - Biomedicines, 2023 - mdpi.com
An aptamer is a single-stranded DNA or RNA that binds to a specific target with high binding
affinity. Aptamers are developed through the process of systematic evolution of ligands by …

Functional Selection of Tau Oligomerization‐Inhibiting Aptamers

B Wang, X Pan, IT Teng, X Li… - Angewandte Chemie …, 2024 - Wiley Online Library
Pathological hyperphosphorylation and aggregation of microtubule‐associated Tau protein
contribute to Alzheimer's Disease (AD) and other related tauopathies. Currently, no cure …

Review on the selection of aptamers and application in paper-based sensors

K Wang, M Wang, T Ma, W Li, H Zhang - Biosensors, 2022 - mdpi.com
An aptamer is a synthetic oligonucleotide, referring to a single-stranded deoxyribonucleic
acid or ribonucleic acid ligand produced by synthesis from outside the body using …

Computational tools for aptamer identification and optimization

D Sun, M Sun, J Zhang, X Lin, Y Zhang, F Lin… - TrAC Trends in …, 2022 - Elsevier
Aptamers are single-stranded DNA or RNA oligonucleotides that can selectively bind to a
specific target. They are generally obtained by SELEX, but the procedure is challenging and …

Artificial intelligence in aptamer–target binding prediction

Z Chen, L Hu, BT Zhang, A Lu, Y Wang, Y Yu… - International journal of …, 2021 - mdpi.com
Aptamers are short single-stranded DNA, RNA, or synthetic Xeno nucleic acids (XNA)
molecules that can interact with corresponding targets with high affinity. Owing to their …