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Advances in nanomaterial-based targeted drug delivery systems
X Cheng, Q **e, Y Sun - Frontiers in bioengineering and …, 2023 - frontiersin.org
Nanomaterial-based drug delivery systems (NBDDS) are widely used to improve the safety
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …
Strategies to improve the EPR effect: a mechanistic perspective and clinical translation
Many efforts have been made to achieve targeted delivery of anticancer drugs to enhance
their efficacy and to reduce their adverse effects. These efforts include the development of …
their efficacy and to reduce their adverse effects. These efforts include the development of …
Optimized strategies of ROS-based nanodynamic therapies for tumor theranostics
Y Di, R Deng, Z Liu, Y Mao, Y Gao, Q Zhao, S Wang - Biomaterials, 2023 - Elsevier
Reactive oxygen species (ROS) play a crucial role in regulating the metabolism of tumor
growth, metastasis, death and other biological processes. ROS-based nanodynamic …
growth, metastasis, death and other biological processes. ROS-based nanodynamic …
Recent advances in dual-and multi-responsive nanomedicines for precision cancer therapy
Nanomedicines have been regarded as a potential approach in the field of cancer treatment
due to their unique advantages. Although improved therapeutic efficacy can be achieved …
due to their unique advantages. Although improved therapeutic efficacy can be achieved …
Reactive oxygen species-sensitive polymeric nanocarriers for synergistic cancer therapy
Z Cao, D Li, J Wang, X Yang - Acta biomaterialia, 2021 - Elsevier
Reactive oxygen species (ROS)-responsive nanocarriers have aroused widespread interest
in recent years. On the one hand, a high ROS level has been detected in many types of …
in recent years. On the one hand, a high ROS level has been detected in many types of …
Current limitations and recent progress in nanomedicine for clinically available photodynamic therapy
Photodynamic therapy (PDT) using oxygen, light, and photosensitizers has been receiving
great attention, because it has potential for making up for the weakness of the existing …
great attention, because it has potential for making up for the weakness of the existing …
pH/ROS dual-responsive supramolecular polypeptide prodrug nanomedicine based on host-guest recognition for cancer therapy
Y Ding, C Wang, Y Ma, L Zhu, B Lu, Y Wang, J Wang… - Acta Biomaterialia, 2022 - Elsevier
Supramolecular nanomedicine assembly combined with polypeptide prodrug could become
a powerful strategy to minimize drug leakage in blood circulation and trigger sufficient drug …
a powerful strategy to minimize drug leakage in blood circulation and trigger sufficient drug …
Exploring novel strategies to improve anti-tumour efficiency: The potential for targeting reactive oxygen species
RS Chasara, TO Ajayi, DM Leshilo, MS Poka, BA Witika - Heliyon, 2023 - cell.com
The cellular milieu in which malignant growths or cancer stem cells reside is known as the
tumour microenvironment (TME). It is the consequence of the interactivity amongst malignant …
tumour microenvironment (TME). It is the consequence of the interactivity amongst malignant …
Overcoming challenges in cancer treatment: nano‐enabled photodynamic therapy as a viable solution
Cancer presents a formidable challenge, necessitating innovative therapies that maximize
effectiveness while minimizing harm to healthy tissues. Nanotechnology has emerged as a …
effectiveness while minimizing harm to healthy tissues. Nanotechnology has emerged as a …
Hypoxia‐responsive tetrameric supramolecular polypeptide nanoprodrugs for combination therapy
Y Ding, W Yu, R Shen, X Zheng… - Advanced …, 2024 - Wiley Online Library
Despite the intense progress of photodynamic and chemotherapy, however, they cannot
prevent solid tumor invasion, metastasis, and relapse, along with inferior efficacy and severe …
prevent solid tumor invasion, metastasis, and relapse, along with inferior efficacy and severe …