Peptide‐based multifunctional nanomaterials for tumor imaging and therapy

C Zhang, W Wu, RQ Li, WX Qiu… - Advanced Functional …, 2018 - Wiley Online Library
During the last decade, peptide‐based nanomaterials are recognized as upcoming
biomedical materials for tumor imaging and therapy. The rapid expansion of peptides and …

Peptide ligand-modified nanomedicines for targeting cells at the tumor microenvironment

A David - Advanced drug delivery reviews, 2017 - Elsevier
Since their initial discovery more than 30 years ago, tumor-homing peptides have become
an increasingly useful tool for targeted delivery of therapeutic and diagnostic agents into …

Rose bengal–amphiphilic peptide conjugate for enhanced photodynamic therapy of malignant melanoma

SK Dhillon, SL Porter, N Rizk, Y Sheng… - Journal of Medicinal …, 2020 - ACS Publications
Malignant melanoma is an aggressive skin cancer with poor survival outcomes for patients
diagnosed at an advanced stage. While targeted serine/threonine-protein kinase B-Raf …

Synthesis and evaluation of multivalent M2pep peptides for targeting alternatively activated M2 macrophages

C Ngambenjawong, M Cieslewicz… - Journal of Controlled …, 2016 - Elsevier
The tumor microenvironment in the majority of cancers is known to favor polarization of
tumor-associated macrophages (TAMs) to alternatively activated M2 phenotype, promoting …

Novel polymeric nanoparticles for intracellular delivery of peptide Cargos: antitumor efficacy of the BCL-2 conversion peptide NuBCP-9

M Kumar, D Gupta, G Singh, S Sharma, M Bhat… - Cancer research, 2014 - AACR
The preclinical development of peptidyl drugs for cancer treatment is hampered by their poor
pharmacologic properties and cell penetrative capabilities in vivo. In this study, we report a …

Self-assembly of cytotoxic peptide conjugated poly (β-amino ester) s for synergistic cancer chemotherapy

ZY Qiao, CY Hou, D Zhang, Y Liu, YX Lin… - Journal of Materials …, 2015 - pubs.rsc.org
Nanotechnology has played an important role in cancer therapy due to the potential
advantages of nano-drugs including enhanced accumulation in the tumor sites, improved …

Two birds, one stone: dual targeting of the cancer cell surface and subcellular mitochondria by the galectin-3-binding peptide G3-C12

W Sun, L Li, L Li, Q Yang, Z Zhang… - Acta Pharmacologica …, 2017 - nature.com
Active tumor-targeting approaches using specific ligands have drawn considerable attention
over the years. However, a single ligand often fails to simultaneously target the cancer cell …

Radiolabeled NGR-Based Heterodimers for Angiogenesis Imaging: A Review of Preclinical Studies

G Trencsényi, G Halmos, Z Képes - Cancers, 2023 - mdpi.com
Simple Summary The increasing prevalence of malignant diseases and related metastases
warrants the need for the establishment of specific diagnostic vectors that ensure timely as …

[HTML][HTML] Development of NGR peptide-based agents for tumor imaging

RE Wang, Y Niu, H Wu, MN Amin… - American journal of nuclear …, 2011 - ncbi.nlm.nih.gov
Molecular imaging allows direct visualization of targets and characterization of cellular
pathways, as long as a high signal/background ratio can be achieved, which requires a …

Angiogenesis regulation by nanocarriers bearing RNA interference

P Ofek, G Tiram, R Satchi-Fainaro - Advanced drug delivery reviews, 2017 - Elsevier
Since the approval of bevacizumab as anti-angiogenic therapy in 2004 by the FDA, an array
of angiogenesis inhibitors have been developed and approved. However, results were …