Peptide‐based multifunctional nanomaterials for tumor imaging and therapy
During the last decade, peptide‐based nanomaterials are recognized as upcoming
biomedical materials for tumor imaging and therapy. The rapid expansion of peptides and …
biomedical materials for tumor imaging and therapy. The rapid expansion of peptides and …
Peptide ligand-modified nanomedicines for targeting cells at the tumor microenvironment
A David - Advanced drug delivery reviews, 2017 - Elsevier
Since their initial discovery more than 30 years ago, tumor-homing peptides have become
an increasingly useful tool for targeted delivery of therapeutic and diagnostic agents into …
an increasingly useful tool for targeted delivery of therapeutic and diagnostic agents into …
Rose bengal–amphiphilic peptide conjugate for enhanced photodynamic therapy of malignant melanoma
SK Dhillon, SL Porter, N Rizk, Y Sheng… - Journal of Medicinal …, 2020 - ACS Publications
Malignant melanoma is an aggressive skin cancer with poor survival outcomes for patients
diagnosed at an advanced stage. While targeted serine/threonine-protein kinase B-Raf …
diagnosed at an advanced stage. While targeted serine/threonine-protein kinase B-Raf …
Synthesis and evaluation of multivalent M2pep peptides for targeting alternatively activated M2 macrophages
C Ngambenjawong, M Cieslewicz… - Journal of Controlled …, 2016 - Elsevier
The tumor microenvironment in the majority of cancers is known to favor polarization of
tumor-associated macrophages (TAMs) to alternatively activated M2 phenotype, promoting …
tumor-associated macrophages (TAMs) to alternatively activated M2 phenotype, promoting …
Novel polymeric nanoparticles for intracellular delivery of peptide Cargos: antitumor efficacy of the BCL-2 conversion peptide NuBCP-9
The preclinical development of peptidyl drugs for cancer treatment is hampered by their poor
pharmacologic properties and cell penetrative capabilities in vivo. In this study, we report a …
pharmacologic properties and cell penetrative capabilities in vivo. In this study, we report a …
Self-assembly of cytotoxic peptide conjugated poly (β-amino ester) s for synergistic cancer chemotherapy
Nanotechnology has played an important role in cancer therapy due to the potential
advantages of nano-drugs including enhanced accumulation in the tumor sites, improved …
advantages of nano-drugs including enhanced accumulation in the tumor sites, improved …
Two birds, one stone: dual targeting of the cancer cell surface and subcellular mitochondria by the galectin-3-binding peptide G3-C12
W Sun, L Li, L Li, Q Yang, Z Zhang… - Acta Pharmacologica …, 2017 - nature.com
Active tumor-targeting approaches using specific ligands have drawn considerable attention
over the years. However, a single ligand often fails to simultaneously target the cancer cell …
over the years. However, a single ligand often fails to simultaneously target the cancer cell …
Radiolabeled NGR-Based Heterodimers for Angiogenesis Imaging: A Review of Preclinical Studies
Simple Summary The increasing prevalence of malignant diseases and related metastases
warrants the need for the establishment of specific diagnostic vectors that ensure timely as …
warrants the need for the establishment of specific diagnostic vectors that ensure timely as …
[HTML][HTML] Development of NGR peptide-based agents for tumor imaging
Molecular imaging allows direct visualization of targets and characterization of cellular
pathways, as long as a high signal/background ratio can be achieved, which requires a …
pathways, as long as a high signal/background ratio can be achieved, which requires a …
Angiogenesis regulation by nanocarriers bearing RNA interference
P Ofek, G Tiram, R Satchi-Fainaro - Advanced drug delivery reviews, 2017 - Elsevier
Since the approval of bevacizumab as anti-angiogenic therapy in 2004 by the FDA, an array
of angiogenesis inhibitors have been developed and approved. However, results were …
of angiogenesis inhibitors have been developed and approved. However, results were …