Synergistic brilliance: engineered bacteria and nanomedicine unite in cancer therapy

Y Zhou, Q Li, Y Wu, W Zhang, L Ding, C Ji… - Advanced …, 2024 - Wiley Online Library
Engineered bacteria are widely used in cancer treatment because live facultative/obligate
anaerobes can selectively proliferate at tumor sites and reach hypoxic regions, thereby …

Marine natural products

AR Carroll, BR Copp, RA Davis, RA Keyzers… - Natural product …, 2019 - pubs.rsc.org
Covering: January to December 2017 This review covers the literature published in 2017 for
marine natural products (MNPs), with 740 citations (723 for the period January to December …

The sponge holobiont in a changing ocean: from microbes to ecosystems

L Pita, L Rix, BM Slaby, A Franke, U Hentschel - Microbiome, 2018 - Springer
The recognition that all macroorganisms live in symbiotic association with microbial
communities has opened up a new field in biology. Animals, plants, and algae are now …

Evolution and diversity of assembly-line polyketide synthases: focus review

A Nivina, KP Yuet, J Hsu, C Khosla - Chemical reviews, 2019 - ACS Publications
Assembly-line polyketide synthases (PKSs) are among the most complex protein
machineries known in nature, responsible for the biosynthesis of numerous compounds …

Visualization of metabolites and microbes at high spatial resolution using MALDI mass spectrometry imaging and in situ fluorescence labeling

P Bourceau, B Geier, V Suerdieck, T Bien… - Nature protocols, 2023 - nature.com
Label-free molecular imaging techniques such as matrix-assisted laser desorption ionization
mass spectrometry imaging (MALDI-MSI) enable the direct and simultaneous map** of …

[HTML][HTML] Metaorganisms in extreme environments: do microbes play a role in organismal adaptation?

C Bang, T Dagan, P Deines, N Dubilier, WJ Duschl… - Zoology, 2018 - Elsevier
From protists to humans, all animals and plants are inhabited by microbial organisms. There
is an increasing appreciation that these resident microbes influence the fitness of their plant …

Spatial metabolomics of in situ host–microbe interactions at the micrometre scale

B Geier, EM Sogin, D Michellod, M Janda… - Nature …, 2020 - nature.com
Spatial metabolomics describes the location and chemistry of small molecules involved in
metabolic phenotypes, defence molecules and chemical interactions in natural communities …

Study of marine microorganism metabolites: New resources for bioactive natural products

N Barzkar, S Sukhikh, O Babich - Frontiers in Microbiology, 2024 - frontiersin.org
The marine environment has remained a source of novel biological molecules with
diversified applications. The ecological and biological diversity, along with a unique physical …

Characterization of a sponge microbiome using an integrative genome-centric approach

JP Engelberts, SJ Robbins, JM de Goeij… - The ISME …, 2020 - academic.oup.com
Marine sponges often host diverse and species-specific communities of microorganisms that
are critical for host health. Previous functional genomic investigations of the sponge …

A genomic view of the microbiome of coral reef demosponges

SJ Robbins, W Song, JP Engelberts, B Glasl… - The ISME …, 2021 - academic.oup.com
Sponges underpin the productivity of coral reefs, yet few of their microbial symbionts have
been functionally characterised. Here we present an analysis of~ 1200 metagenome …