Ultrasound‐controlled drug release and drug activation for cancer therapy
Traditional chemotherapy suffers from severe toxicity and side effects that limit its maximum
application in cancer therapy. To overcome this challenge, an ideal treatment strategy would …
application in cancer therapy. To overcome this challenge, an ideal treatment strategy would …
Covalent mechanochemistry: theoretical concepts and computational tools with applications to molecular nanomechanics
J Ribas-Arino, D Marx - Chemical reviews, 2012 - ACS Publications
In the following section, we will recapitulate selected experimental milestones through the
eyes of the theoretician, which, in our opinion, significantly advanced the field of covalent …
eyes of the theoretician, which, in our opinion, significantly advanced the field of covalent …
Mechanical control of nanomaterials and nanosystems
In situations of power outage or shortage, such as periods just following a seismic disaster,
the only reliable power source available is the most fundamental of forces ie, manual …
the only reliable power source available is the most fundamental of forces ie, manual …
Force-rate characterization of two spiropyran-based molecular force probes
GR Gossweiler, TB Kouznetsova… - Journal of the American …, 2015 - ACS Publications
The mechanically accelerated ring-opening reaction of spiropyran to a colored merocyanine
provides a useful method by which to image the molecular scale stress/strain distribution …
provides a useful method by which to image the molecular scale stress/strain distribution …
The tension-activated carbon–carbon bond
Mechanical force drives distinct chemical reactions; yet, its vectoral nature results in
complicated coupling with reaction trajectories. Here, we utilize a physical organic model …
complicated coupling with reaction trajectories. Here, we utilize a physical organic model …
Polymer mechanochemistry-enabled pericyclic reactions
Over the past decades, it became clear that next to heat and light, pericyclic reactions can be
induced mechanochemically when the reacting motifs are embedded as latent force …
induced mechanochemically when the reacting motifs are embedded as latent force …
From molecular mechanochemistry to stress-responsive materials
Current activity in, and future prospects for, the incorporation of mechanochemically active
functional groups (“mechanophores”) into polymers is reviewed. This area of research is …
functional groups (“mechanophores”) into polymers is reviewed. This area of research is …
Advances in quantum mechanochemistry: electronic structure methods and force analysis
In quantum mechanochemistry, quantum chemical methods are used to describe molecules
under the influence of an external force. The calculation of geometries, energies, transition …
under the influence of an external force. The calculation of geometries, energies, transition …
The cascade unzip** of ladderane reveals dynamic effects in mechanochemistry
Force can induce remarkable non-destructive transformations along a polymer, but we have
a limited understanding of the energy transduction and product distribution in tandem …
a limited understanding of the energy transduction and product distribution in tandem …
Controlling reactivity by geometry in retro-Diels–Alder reactions under tension
R Stevenson, G De Bo - Journal of the American Chemical …, 2017 - ACS Publications
Mechanical force, with its ability to distort, bend, and stretch chemical bonds, is unique in the
way it activates chemical reactions. In polymer mechanochemistry, the force is transduced in …
way it activates chemical reactions. In polymer mechanochemistry, the force is transduced in …