[HTML][HTML] Alzheimer's disease pathophysiology in the retina
The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …
[HTML][HTML] Neuroprotection in glaucoma: mechanisms beyond intraocular pressure lowering
Glaucoma is a common, complex, multifactorial neurodegenerative disease characterized
by progressive dysfunction and then loss of retinal ganglion cells, the output neurons of the …
by progressive dysfunction and then loss of retinal ganglion cells, the output neurons of the …
Terminal complement pathway activation drives synaptic loss in Alzheimer's disease models
Complement is involved in developmental synaptic pruning and pathological synapse loss
in Alzheimer's disease. It is posited that C1 binding initiates complement activation on …
in Alzheimer's disease. It is posited that C1 binding initiates complement activation on …
Salvianolic acid B ameliorates retinal deficits in an early-stage alzheimer's disease mouse model through downregulating bace1 and Aβ Generation
M Wang, S Zhang, X Liu, P Wang, Y Zhu… - Acta Pharmacologica …, 2023 - nature.com
Alzheimer's disease (AD) is a neurodegenerative disease with subtle onset, early diagnosis
remains challenging. Accumulating evidence suggests that the emergence of retinal …
remains challenging. Accumulating evidence suggests that the emergence of retinal …
Homocysteine and age-related central nervous system diseases: role of inflammation
Hyperhomocysteinemia (HHcy) is remarkably common among the aging population. The
relation between HHcy and the development of neurodegenerative diseases, such as …
relation between HHcy and the development of neurodegenerative diseases, such as …
[HTML][HTML] The retina: A window in which to view the pathogenesis of Alzheimer's disease
J Zhang, L Shi, Y Shen - Ageing Research Reviews, 2022 - Elsevier
Alzheimer's disease (AD) is the most familiar type of dementia affecting elderly populations
worldwide. Studies of AD patients and AD transgenic mice have revealed alterations in the …
worldwide. Studies of AD patients and AD transgenic mice have revealed alterations in the …
The retinal ganglion cell layer reflects neurodegenerative changes in cognitively unimpaired individuals
A López-de-Eguileta, S López-García, C Lage… - Alzheimer's research & …, 2022 - Springer
Background To evaluate a wide range of optical coherence tomography (OCT) parameters
for possible application as a screening tool for cognitively healthy individuals at risk of …
for possible application as a screening tool for cognitively healthy individuals at risk of …
Assessment of Lab4P probiotic effects on cognition in 3xTg-AD Alzheimer's disease model mice and the SH-SY5Y neuronal cell line
TS Webberley, RJ Bevan, J Kerry-Smith, J Dally… - International Journal of …, 2023 - mdpi.com
Aging and metabolic syndrome are associated with neurodegenerative pathologies
including Alzheimer's disease (AD) and there is growing interest in the prophylactic potential …
including Alzheimer's disease (AD) and there is growing interest in the prophylactic potential …
Prophylactic nicotinamide treatment protects from rotenone-induced neurodegeneration by increasing mitochondrial content and volume
Leber's hereditary optic neuropathy (LHON) is driven by mtDNA mutations affecting
Complex I presenting as progressive retinal ganglion cell dysfunction usually in the absence …
Complex I presenting as progressive retinal ganglion cell dysfunction usually in the absence …
Retinal dysfunction in Alzheimer's disease and implications for biomarkers
C Liao, J Xu, Y Chen, NY Ip - Biomolecules, 2021 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that manifests as
cognitive deficits and memory decline, especially in old age. Several biomarkers have been …
cognitive deficits and memory decline, especially in old age. Several biomarkers have been …