Corticosteroid‐induced chromatin loop dynamics at the FKBP5 gene

C Wang, F Manders, L Groh… - Annals of the New …, 2023 - Wiley Online Library
Abstract FKBP5 is a 115‐kb‐long glucocorticoid‐inducible gene implicated in psychiatric
disorders. To investigate the complexities of chromatin interaction frequencies at the FKBP5 …

Profiling chromatin accessibility responses in human neutrophils with sensitive pathogen detection

N Ram-Mohan, SA Thair… - Life Science …, 2021 - life-science-alliance.org
Sepsis, sequela of bloodstream infections and dysregulated host responses, is a leading
cause of death globally. Neutrophils tightly regulate responses to pathogens to prevent …

The Role of CTCF-Mediated Chromatin Loo** in Enhancer-Promoter Communication

C Logie - Epigenetics in Biological Communication, 2024 - Springer
In vertebrates, gene transcription is performed by generic eukaryotic molecular machinery
under influence of sequence-specific DNA-binding transcription factors that control gene …

Modelling the 3D-Genome: The development of network theory approaches to characterise and predict active enhancers

MMS Heer - 2022 - theses.ncl.ac.uk
Gene regulation is an important mechanism that ensures the correct functioning of a cell and
is generally orchestrated by gene regulatory elements such as transcriptional enhancers …

Integrative profiling of early host chromatin accessibility responses in human neutrophils with sensitive pathogen detection

N Ram-Mohan, SA Thair, UM Litzenburger, S Cogill… - bioRxiv, 2020 - biorxiv.org
Sepsis is a leading cause of death globally where neutrophils respond to pathogens via
tightly regulated antimicrobial effectors. Combining early neutrophilic responses and …

[PDF][PDF] Míra citrulinace histonu H3 ve spojitosti s fyziologickými projevy neutrofilů a typem jejich buněčné smrti

A Hronová - is.muni.cz
Zralé neutrofilní granulocyty jsou vnímány jako plně diferencované imunitní buňky, které j
sou připravené na setkání s cizorodým agens pro zahaj ení fagocytózy, produkci reaktivních …