HIV-associated neurocognitive disorder—pathogenesis and prospects for treatment
In the past two decades, several advancements have improved the care of HIV-infected
individuals. Most importantly, the development and deployment of combination antiretroviral …
individuals. Most importantly, the development and deployment of combination antiretroviral …
[HTML][HTML] Mental health and HIV/AIDS: the need for an integrated response
Tremendous biomedical advancements in HIV prevention and treatment have led to
aspirational efforts to end the HIV epidemic. However, this goal will not be achieved without …
aspirational efforts to end the HIV epidemic. However, this goal will not be achieved without …
HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors
Combination antiretroviral therapy (CART) has greatly reduced medical morbidity and
mortality with HIV infection, but high rates of HIV-associated neurocognitive disorders …
mortality with HIV infection, but high rates of HIV-associated neurocognitive disorders …
Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives
DJ Baker, RC Petersen - The Journal of clinical …, 2018 - Am Soc Clin Investig
Along with a general decline in overall health, most chronic degenerative human diseases
are inherently associated with increasing age. Age-associated cognitive impairments and …
are inherently associated with increasing age. Age-associated cognitive impairments and …
Global prevalence and burden of HIV-associated neurocognitive disorder: a meta-analysis
Objective To characterize the prevalence and burden of HIV-associated neurocognitive
disorder (HAND) and assess associated factors in the global population with HIV. Methods …
disorder (HAND) and assess associated factors in the global population with HIV. Methods …
Neuroimmune axes of the blood–brain barriers and blood–brain interfaces: bases for physiological regulation, disease states, and pharmacological interventions
Central nervous system (CNS) barriers predominantly mediate the immune-privileged status
of the brain, and are also important regulators of neuroimmune communication. It is …
of the brain, and are also important regulators of neuroimmune communication. It is …
Plasma concentration of the neurofilament light protein (NFL) is a biomarker of CNS injury in HIV infection: a cross-sectional study
M Gisslén, RW Price, U Andreasson, N Norgren… - …, 2016 - thelancet.com
Background Cerebrospinal fluid (CSF) neurofilament light chain protein (NFL) is a sensitive
marker of neuronal injury in a variety of neurodegenerative conditions, including the CNS …
marker of neuronal injury in a variety of neurodegenerative conditions, including the CNS …
Prevalence of HIV-associated neurocognitive disorders in the Multicenter AIDS Cohort Study
Objective: To evaluate the frequency of HIV-associated neurocognitive disorder (HAND) in
HIV+ individuals and determine whether the frequency of HAND changed over 4 years of …
HIV+ individuals and determine whether the frequency of HAND changed over 4 years of …
HIV-associated neurocognitive disorder
Neurological involvement in HIV is often associated with cognitive impairment. Although
severe and progressive neurocognitive impairment has become rare in HIV clinics in the era …
severe and progressive neurocognitive impairment has become rare in HIV clinics in the era …
Central nervous system viral invasion and inflammation during acute HIV infection
V Valcour, T Chalermchai, N Sailasuta… - The Journal of …, 2012 - academic.oup.com
Background. Understanding the earliest central nervous system (CNS) events during human
immunodeficiency virus (HIV) infection is crucial to knowledge of neuropathogenesis, but …
immunodeficiency virus (HIV) infection is crucial to knowledge of neuropathogenesis, but …