[HTML][HTML] The role of plastic concerning the sustainable development goals: The literature point of view

FDB de Sousa - Cleaner and Responsible Consumption, 2021 - Elsevier
There is no doubt about the importance of plastic in modern society. It has revolutionized our
daily lives and several industrial sectors. It is widely present in our lives, from the beginning …

Lipid nanodiscs for high-resolution NMR studies of membrane proteins

U Günsel, F Hagn - Chemical Reviews, 2021 - ACS Publications
Membrane proteins (MPs) play essential roles in numerous cellular processes. Because
around 70% of the currently marketed drugs target MPs, a detailed understanding of their …

Oligomeric organization of membrane proteins from native membranes at nanoscale spatial and single-molecule resolution

G Walker, C Brown, X Ge, S Kumar… - Nature …, 2024 - nature.com
The oligomeric organization of membrane proteins in native cell membranes is a critical
regulator of their function. High-resolution quantitative measurements of oligomeric …

Electroneutral Polymer Nanodiscs Enable Interference‐Free Probing of Membrane Proteins in a Lipid‐Bilayer Environment

D Glueck, A Grethen, M Das, OP Mmeka, EP Patallo… - Small, 2022 - Wiley Online Library
Membrane proteins can be examined in near‐native lipid‐bilayer environments with the
advent of polymer‐encapsulated nanodiscs. These nanodiscs self‐assemble directly from …

[HTML][HTML] Structural biology of endogenous membrane protein assemblies in native nanodiscs

CJ Brown, C Trieber, M Overduin - Current Opinion in Structural Biology, 2021 - Elsevier
The advent of amphiphilic copolymers enables integral membrane proteins to be solubilized
into stable 10–30 nm native nanodiscs to resolve their multisubunit structures, post …

Sulfonated polystyrenes: pH and Mg2+-insensitive amphiphilic copolymers for detergent-free membrane protein isolation

M Janata, S Gupta, E Čadová, P Angelisová… - European Polymer …, 2023 - Elsevier
Amphiphilic polymers are increasingly applied in the detergent-free isolation and functional
studies of membrane proteins. However, the carboxylate group present in the structure of …

Methods for the solubilisation of membrane proteins: the micelle-aneous world of membrane protein solubilisation

G Ratkeviciute, BF Cooper… - Biochemical Society …, 2021 - portlandpress.com
The solubilisation of membrane proteins (MPs) necessitates the overlap of two contradictory
events; the extraction of MPs from their native lipid membranes and their subsequent …

Synthesis and evaluation of a library of alternating amphipathic copolymers to solubilize and study membrane proteins

AH Kopf, O Lijding, BOW Elenbaas… - …, 2022 - ACS Publications
Amphipathic copolymers such as poly (styrene-maleic acid)(SMA) are promising tools for the
facile extraction of membrane proteins (MPs) into native nanodiscs. Here, we designed and …

Understanding the structural pathways for lipid nanodisc formation: how styrene maleic acid copolymers induce membrane fracture and disc formation

VA Bjørnestad, M Orwick-Rydmark, R Lund - Langmuir, 2021 - ACS Publications
Lipid nanodiscs formed by mixtures of styrene maleic acid (SMA) copolymers and lipid
membranes are important tools for studying membrane proteins in many biotechnological …

Charge‐Stabilized Nanodiscs as a New Class of Lipid Nanoparticles

IS Pires, A Hostetler, G Covarrubias, IS Carlo… - Advanced …, 2024 - Wiley Online Library
Nanoparticles have the potential to improve disease treatment and diagnosis due to their
ability to incorporate drugs, alter pharmacokinetics, and enable tissue targeting. While …