Cells have the ability to respond to various types of environmental cues, and in many cases
these cues induce directed cell migration towards or away from these signals. How cells …

Direct-current (DC) electric fields are present in all develo** and regenerating animal
tissues, yet their existence and potential impact on tissue repair and development are …

Formyl peptide receptors (FPRs) are a small group of seven-transmembrane domain, G
protein-coupled receptors that are expressed mainly by mammalian phagocytic leukocytes …

▪ Abstract The 3-phosphorylated inositol lipids fulfill roles as second messengers by
interacting with the lipid binding domains of a variety of cellular proteins. Such interactions …

During random locomotion, human neutrophils and Dictyostelium discoideum amoebae
repeatedly extend and retract cytoplasmic processes. During directed cell migration …

In eukaryotic cells directional sensing is mediated by heterotrimeric guanine nucleotide–
binding protein (G protein)–linked signaling pathways. In Dictyostelium discoideum …

The trafficking of leukocytes into and within lymphoid and peripheral tissues is central to
immune cell development, immunosurveillance and effector function. Interstitial leukocyte …

During neuroinflammation, activated microglial cells migrate toward dying neurons, where
they exacerbate local cell damage. The signaling molecules that trigger microglial cell …

Morphologic polarity is necessary for chemotaxis of mammalian cells. As a probe of
intracellular signals responsible for this asymmetry, the pleckstrin homology domain of the …

Biomolecule gradients have been shown to play roles in a wide range of biological
processes including development, inflammation, wound healing, and cancer metastasis …