[HTML][HTML] Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications

V Vrablova, N Kosutova, A Blsakova, A Bertokova… - Biotechnology …, 2023 - Elsevier
This review provides a comprehensive overview of our understanding of the role that
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …

Protein glycosylation in extracellular vesicles: Structural characterization and biological functions

J Macedo-da-Silva, VF Santiago… - Molecular …, 2021 - Elsevier
Extracellular vesicles (EVs) are lipid bilayer-enclosed particles involved in intercellular
communication, delivery of biomolecules from donor to recipient cells, cellular disposal and …

A review on the use of extracellular vesicles for the delivery of drugs and biological therapeutics

SJ Amina, T Azam, F Dagher, B Guo - Expert Opinion on Drug …, 2024 - Taylor & Francis
Introduction Exosomes, a type of extracellular vesicles, are effective tools for delivering small-
molecule drugs and biological therapeutics into cells and tissues. Surface modifications with …

Conventional and nonconventional sources of exosomes–isolation methods and influence on their downstream biomedical application

O Janouskova, R Herma, A Semeradtova… - Frontiers in Molecular …, 2022 - frontiersin.org
Despite extensive study of extracellular vesicles (EVs), specifically exosomes (EXs) as
biomarkers, important modulators of physiological or pathological processes, or therapeutic …

Extracellular vesicles in veterinary medicine

V Moccia, A Sammarco, L Cavicchioli, M Castagnaro… - Animals, 2022 - mdpi.com
Simple Summary Extracellular vesicles (EVs) are small vesicles released by human and
animal cells, parasites, microorganisms, and plants. They travel within bodily fluids …

Exosomes on the border of species and kingdom intercommunication

CMAP Schuh, J Cuenca, F Alcayaga-Miranda… - Translational …, 2019 - Elsevier
Over the last decades exosomes have become increasingly popular in the field of medicine.
While until recently they were believed to be involved in the removal of obsolete particles …

The functions of CAP superfamily proteins in mammalian fertility and disease

AS Gaikwad, J Hu, DG Chapple… - Human reproduction …, 2020 - academic.oup.com
BACKGROUND Members of the cysteine-rich secretory proteins (CRISPS), antigen 5 (Ag5)
and pathogenesis-related 1 (Pr-1)(CAP) superfamily of proteins are found across the …

Proteomic identification and quantification of snake venom biomarkers in venom and plasma extracellular vesicles

NK Willard, E Salazar, FA Oyervides, CS Wiebe… - Toxins, 2021 - mdpi.com
The global exploration of snakebites requires the use of quantitative omics approaches to
characterize snake venom as it enters into the systemic circulation. These omics approaches …

Utilisation of compounds from venoms in drug discovery

CM Trim, LJ Byrne, SA Trim - Progress in Medicinal Chemistry, 2021 - Elsevier
Difficult drug targets are becoming the normal course of business in drug discovery,
sometimes due to large interacting surfaces or only small differences in selectivity regions …

Bee Venom PLA2 versus Snake Venom PLA2: Evaluation of Structural and Functional Properties

L Bitar, D Jundia, M Rima, JM Sabatier… - Venoms and …, 2022 - benthamdirect.com
Phospholipases A2 enzymes are found in many mammalian tissues and in animal venoms.
Those present in bee venom (bvPLA2) and snake venom (svPLA2) have been studied more …