[HTML][HTML] Salivary metabolomics: from diagnostic biomarker discovery to investigating biological function

A Gardner, G Carpenter, PW So - Metabolites, 2020 - mdpi.com
Metabolomic profiling of biofluids, eg, urine, plasma, has generated vast and ever-
increasing amounts of knowledge over the last few decades. Paradoxically, metabolomic …

Saliva based liquid biopsies in head and neck cancer: how far are we from the clinic?

A Patel, S Patel, P Patel, V Tanavde - Frontiers in oncology, 2022 - frontiersin.org
Head and neck cancer (HNC) remains to be a major cause of mortality worldwide because
of confounding factors such as late-stage tumor diagnosis, loco-regional aggressiveness …

The human saliva metabolome

ZT Dame, F Aziat, R Mandal, R Krishnamurthy… - Metabolomics, 2015 - Springer
Saliva is a clear, watery biofluid produced by the salivary glands to protect and lubricate the
oral cavity. While mostly composed of water (99%), the chemical composition of saliva is …

Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles

M Sugimoto, DT Wong, A Hirayama, T Soga, M Tomita - Metabolomics, 2010 - Springer
Saliva is a readily accessible and informative biofluid, making it ideal for the early detection
of a wide range of diseases including cardiovascular, renal, and autoimmune diseases, viral …

Analytical strategies in metabonomics

EM Lenz, ID Wilson - Journal of proteome research, 2007 - ACS Publications
To perform metabonomics investigations, it is necessary to generate comprehensive
metabolite profiles for complex samples such as biofluids and tissue/tissue extracts …

NMR spectroscopy of biofluids

JC Lindon, JK Nicholson, JR Everett - Annual reports on NMR spectroscopy, 1999 - Elsevier
Publisher Summary This chapter reviews that the analysis of biofluids provides a unique
window into the biochemical status of a living organism since the composition of a given …

[HTML][HTML] Effect of acute dietary standardization on the urinary, plasma, and salivary metabolomic profiles of healthy humans

MC Walsh, L Brennan, JPG Malthouse… - The American journal of …, 2006 - Elsevier
Background: Metabolomics in human nutrition research is faced with the challenge that
changes in metabolic profiles resulting from diet may be difficult to differentiate from normal …

[書籍][B] Metabolome analysis: an introduction

SG Villas-Boas, J Nielsen, J Smedsgaard… - 2007 - books.google.com
Providing information on the main approaches for the analysis of metabolites, this textbook:
Covers basic methodologies in sample preparation and separation techniques, as well as …

Metabolomics of human amniotic fluid and maternal plasma during normal pregnancy

M Orczyk-Pawilowicz, E Jawien, S Deja, L Hirnle… - PloS one, 2016 - journals.plos.org
Metabolic profiles of amniotic fluid and maternal blood are sources of valuable information
about fetus development and can be potentially useful in diagnosis of pregnancy disorders …

Clinical reversal of root caries using ozone, double‐blind, randomised, controlled 18‐month trial

J Holmes - Gerodontology, 2003 - Wiley Online Library
Objective: To assess the effect of an ozone delivery system, combined with the daily use of a
remineralising patient kit, on the clinical severity of non‐cavitated leathery primary root …