Light at night disrupts biological clocks, calendars, and immune function

WH Walker, JR Bumgarner, DD Becker-Krail… - Seminars in …, 2022 - Springer
Light at night is a pervasive problem in our society; over 80% of the world's population
experiences significant light pollution. Exacerbating this issue is the reality that artificially lit …

Circadian disruption and consequences on innate immunity and inflammatory response

V Jerigova, M Zeman, M Okuliarova - International Journal of Molecular …, 2022 - mdpi.com
Circadian rhythms control almost all aspects of physiology and behavior, allowing temporal
synchrony of these processes between each other, as well as with the external environment …

Circadian disruption: from mouse models to molecular mechanisms and cancer therapeutic targets

Y Wang, H Guo, F He - Cancer and Metastasis Reviews, 2023 - Springer
The circadian clock is a timekee** system for numerous biological rhythms that contribute
to the regulation of numerous homeostatic processes in humans. Disruption of circadian …

The recent progress of myeloid‐derived suppressor cell and its targeted therapies in cancers

R Ren, C **ong, R Ma, Y Wang, T Yue, J Yu… - MedComm, 2023 - Wiley Online Library
Myeloid‐derived suppressor cells (MDSCs) are an immature group of myeloid‐derived cells
generated from myeloid cell precursors in the bone marrow. MDSCs appear almost …

The role of myeloid-derived suppressor cells in rheumatoid arthritis: An update

JG Navashenaq, AG Shabgah, M Hedayati-Moghadam… - Life Sciences, 2021 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease that generally affects the joints. In the
late stages of the disease, it can be associated with several complications. Although the …

Roles of myeloid-derived suppressor cell subpopulations in autoimmune arthritis

M Li, D Zhu, T Wang, X **a, J Tian, S Wang - Frontiers in immunology, 2018 - frontiersin.org
Emerging evidence suggests the promise of the use of myeloid-derived suppressor cells
(MDSCs) in inflammatory disorders based on their unique immune-intervention properties …

Circadian clock and complement immune system—complementary control of physiology and pathology?

P Shivshankar, B Fekry, K Eckel-Mahan… - Frontiers in cellular and …, 2020 - frontiersin.org
Mammalian species contain an internal circadian (ie, 24-h) clock that is synchronized to the
day and night cycles. Large epidemiological studies, which are supported by carefully …

MDSCs might be “Achilles heel” for eradicating CSCs

T Yang, N Liang, J Li, P Hu, Q Huang, Z Zhao… - Cytokine & Growth …, 2022 - Elsevier
During tumor initiation and progression, the complicated role of immune cells in the tumor
immune microenvironment remains a concern. Myeloid-derived suppressor cells (MDSCs) …

Diverse functions of myeloid-derived suppressor cells in autoimmune diseases

X **ong, Y Zhang, Y Wen - Immunologic Research, 2024 - Springer
Since myeloid-derived suppressor cells (MDSCs) were found suppressing immune
responses in cancer and other pathological conditions, subsequent researchers have …

Dysfunctional circadian clock accelerates cancer metastasis by intestinal microbiota triggering accumulation of myeloid-derived suppressor cells

JL Liu, X Xu, Y Rixiati, CY Wang, HL Ni, WS Chen… - Cell Metabolism, 2024 - cell.com
Circadian homeostasis in mammals is a key intrinsic mechanism for responding to the
external environment. However, the interplay between circadian rhythms and the tumor …