Critical illness weakness, polyneuropathy and myopathy: diagnosis, treatment, and long-term outcomes

N Latronico, FA Rasulo, M Eikermann, S Piva - Critical Care, 2023 - Springer
Background Severe weakness associated with critical illness (CIW) is common. This
narrative review summarizes the latest scientific insights and proposes a guide for clinicians …

Current therapeutic targets in cancer cachexia: a pathophysiologic approach

KC Kadakia, JM Hamilton-Reeves… - American Society of …, 2023 - ascopubs.org
Significant progress in our understanding of cancer cachexia has occurred in recent years.
Despite these advances, no pharmacologic agent has achieved US Food and Drug …

Early in-bed cycle ergometry in mechanically ventilated patients

ME Kho, S Berney, AM Pastva, L Kelly, JC Reid… - NEJM …, 2024 - evidence.nejm.org
Background Critical illness requiring invasive mechanical ventilation can precipitate
important functional disability, contributing to multidimensional morbidity following …

[HTML][HTML] Survival≠ recovery: a narrative review of post-intensive care syndrome

E Schwitzer, KS Jensen, L Brinkman, L DeFrancia… - CHEST Critical …, 2023 - Elsevier
Surviving critical illness does not always equate to recovery, with its aftermath frequently
complicated by post-intensive care syndrome (PICS). This syndrome consists of a collection …

Association of muscle wasting with mortality risk among adults: A systematic review and meta‐analysis of prospective studies

HH Zhou, Y Liao, Z Peng, F Liu… - Journal of Cachexia …, 2023 - Wiley Online Library
The relationship between muscle wasting and mortality risk in the general population
remains unclear. Our study was conducted to examine and quantify the associations …

Guideline on positioning and early mobilisation in the critically ill by an expert panel

SJ Schaller, FT Scheffenbichler, T Bein… - Intensive Care …, 2024 - Springer
A scientific panel was created consisting of 23 interdisciplinary and interprofessional experts
in intensive care medicine, physiotherapy, nursing care, surgery, rehabilitative medicine …

[HTML][HTML] Study protocol for TARGET protein: the effect of augmented administration of enteral protein to critically ill adults on clinical outcomes: a cluster randomised …

MJ Summers, SC Lee-anne, R Bellomo… - Critical Care and …, 2023 - Elsevier
Background It is unknown whether increasing dietary protein to 1.2–2.0 g/kg/day as
recommended in international guidelines compared to current practice improves outcomes …