MicroRNA delivery through nanoparticles

SWL Lee, C Paoletti, M Campisi, T Osaki… - Journal of Controlled …, 2019 - Elsevier
MicroRNAs (miRNAs) are attracting a growing interest in the scientific community due to
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …

Nanoparticles and innate immunity: new perspectives on host defence

D Boraschi, P Italiani, R Palomba, P Decuzzi… - Seminars in …, 2017 - Elsevier
The innate immune system provides the first line of defence against foreign microbes and
particulate materials. Engineered nanoparticles can interact with the immune system in …

[HTML][HTML] Targeting immune cells for cancer therapy

SY Gun, SWL Lee, JL Sieow, SC Wong - Redox biology, 2019 - Elsevier
Recent years have seen a renaissance in the research linking inflammation and cancer with
immune cells playing a central role in smouldering inflammation in the tumor …

Current advances in the use of exosomes, liposomes, and bioengineered hybrid nanovesicles in cancer detection and therapy

A Mukherjee, B Bisht, S Dutta, MK Paul - Acta Pharmacologica Sinica, 2022 - nature.com
Three major approaches of cancer therapy can be enunciated as delivery of biotherapeutics,
tumor image analysis, and immunotherapy. Liposomes, artificial fat bubbles, are long known …

Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets

KMT Arif, EK Elliott, LM Haupt, LR Griffiths - Cancers, 2020 - mdpi.com
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …

Nanocarriers for the delivery of medical, veterinary, and agricultural active ingredients

PL Chariou, OA Ortega-Rivera, NF Steinmetz - Acs Nano, 2020 - ACS Publications
Nanocarrier-based delivery systems can be used to increase the safety and efficacy of active
ingredients in medical, veterinary, or agricultural applications, particularly when such …

New opportunities for nanoparticles in cancer immunotherapy

W Park, YJ Heo, DK Han - Biomaterials research, 2018 - spj.science.org
Background Recently, cancer immunotherapy has become standard for cancer treatment.
Immunotherapy not only treats primary tumors, but also prevents metastasis and recurrence …

Precision cancer nanotherapy: evolving role of multifunctional nanoparticles for cancer active targeting

A Ahmad, F Khan, RK Mishra… - Journal of medicinal …, 2019 - ACS Publications
Nanoparticles with multifunctionality are being designed and formulated to overcome
various limitations of drugs as well as conventional drug delivery systems. Engineered …

Nanomedicines inhibiting tumor metastasis and recurrence and their clinical applications

X Kong, R Cheng, J Wang, Y Fang, KC Hwang - Nano Today, 2021 - Elsevier
Tumor metastasis and recurrence is one of the biggest problems in curing cancers. Due to
the difficulty in complete removal of the primary tumor in traditional surgeries and the poor …

Engineering nanoparticle strategies for effective cancer immunotherapy

HY Yoon, ST Selvan, Y Yang, MJ Kim, DK Yi, IC Kwon… - Biomaterials, 2018 - Elsevier
Cancer immunotherapy has been emerging in recent years, due to the inherent nature of the
immune system. Although recent successes of immunotherapeutics in clinical application …