TRanscription and EXport (TREX) is a conserved multisubunit complex essential for
embryogenesis, organogenesis and cellular differentiation throughout life. By linking …

Transport of messenger RNA (mRNA) from the nucleus to the cytoplasm is an essential step
of eukaryotic gene expression. In the cell nucleus, a precursor mRNA undergoes a series of …

THOC5, a member of the THO complex, is essential for the 3′ processing of some inducible
genes, the export of a subset of mRNAs and stem cell survival. Here we show that THOC5 …

RNA helicases constitute a large protein family implicated in cellular RNA homeostasis and
disease development. Here, we show that the RNA helicase IGHMBP2, linked to the …

Synaptic vesicle and active zone proteins are required for synaptogenesis. The molecular
mechanisms for coordinated synthesis of these proteins are not understood. Using forward …

The ability of live yeasts to modulate pig intestinal cell signals in response to infection with
Escherichia coli F4ac (ETEC) has not been studied in-depth. The aim of this trial was to …

RNA binding proteins (RBPs) are aberrantly expressed in a tissue-specific manner across
many tumors. These proteins, which play a vital role in post-transcriptional gene regulation …

Triple-negative breast cancers (TNBCs) are difficult to cure and currently lack of effective
treatment strategies. Cancer stem cells (CSCs) are highly associated with the poor clinical …

Transcription of immediate early genes (IEGs) in response to extrinsic and intrinsic signals is
tightly regulated at multiple stages. It is known that untranslated regions of the RNA can play …

The integrity and proper expression of genomes are safeguarded by DNA and RNA
surveillance pathways. While many RNA surveillance factors have additional functions in the …