Oxidative stress is a consequence of the use of oxygen in aerobic respiration by living
organisms and is denoted as a persistent condition of an imbalance between the generation …

Advanced glycation end products (AGEs) are proteins or lipids that become glycated after
exposure to sugars. AGEs are prevalent in the diabetic vasculature and contribute to the …

Significance: Fibroblasts play a critical role in normal wound healing. Various extracellular
matrix (ECM) components, including collagens, fibrin, fibronectin, proteoglycans …

Wound healing is a well-tuned biological process, which is achieved via consecutive and
overlap** phases including hemostasis, inflammatory-related events, cell proliferation and …

Diabetes mellitus is a common endocrine disorder characterised by hyperglycaemia and
predisposes to chronic complications affecting the eyes, blood vessels, nerves and kidneys …

Diabetes mellitus (a group of metabolic disorders characterized by hyperglycemia) and
periodontitis (a microbially induced inflammatory disorder that affects the supporting …

Advanced glycation end products (AGEs), S100/calgranulins, HMGB1-proteins, amyloid-β
peptides, and the family of β-sheet fibrils have been shown to contribute to a number of …

AGEs Tumor biology Amphoterin albumin prepared in vitro (7). Its extracellular domain
consists of three immunoglobulin-like regions, one “V”-type followed by two “C”-type (8) …

The receptor for advanced glycation end-products (RAGE) is a multiligand pattern
recognition receptor implicated in diverse chronic inflammatory states. RAGE binds and …

Aging is the progressive accumulation of damage to an organism over time leading to
disease and death. Aging research has been very intensive in the last years aiming at …