The literature on large‐scale resting‐state functional brain networks across the adult
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …

Parkinson's disease presents several practical challenges: it can be difficult to distinguish
from atypical parkinsonian syndromes, clinical ratings can be insensitive as markers of …

Metabolic connectivity is a valuable concept in the fast-develo** field of brain connectivity,
at least as reasonable as functional connectivity of functional MRI. So far, the value of …

In the past two decades brain connectomics has evolved into a major concept in
neuroscience. However, the current perspective on brain connectivity and how it underpins …

A progressive loss of dopamine neurons in the substantia nigra (SN) is considered the main
feature of idiopathic Parkinson's disease (PD). Recent neuropathological evidence however …

Purpose Positron emission tomography (PET) with 18 F-fluorodeoxyglucose (FDG) reveals
altered cerebral metabolism in individuals with mild cognitive impairment (MCI) and …

Positron emission tomography (PET) represents a unique molecular tool to get in vivo
access to a wide spectrum of biological and neuropathological processes, of crucial …

Aim We aimed to investigate the impact of microglial activity and microglial FDG uptake on
metabolic connectivity, since microglial activation states determine FDG–PET alterations …

To explore the effects of PD pathology on brain connectivity, we characterized with an
emergent computational approach the brain metabolic connectome using [18F] FDG-PET in …

Functional magnetic resonance and diffusion weighted imaging have so far made a major
contribution to delineation of the brain connectome at the macroscale. While functional …