Asymmetric catalysis plays a key role in modern synthetic organic chemistry, with synthetic
catalysts and enzymes being the two available options. During the latter part of the last …

During the recent past years, tremendous efforts have been made to establish
enantioselective routes for the preparation of enantiomerically pure compounds due to their …

Living organisms rely on simultaneous reactions catalysed by mutually compatible and
selective enzymes to synthesize complex natural products and other metabolites. To …

Intermolecular C–C bond-forming reactions are underdeveloped transformations in the field
of biocatalysis. Here we report a photoenzymatic intermolecular hydroalkylation of olefins …

When challenged by a difficult reduction reaction, a chemist should always also consider
biocatalysis in synthesis planning. The inherent selectivity of enzymes has been known for …

The search for affordable, green biocatalytic processes is a challenge for chemicals
manufacture. Redox biotransformations are potentially attractive, but they rely on unstable …

The old yellow enzyme (OYE) family is a large group of flavin‐dependent redox biocatalysts
with major applications in the industrial reduction of activated alkenes. These enzymes have …

Biological production of chemicals often requires the use of cellular cofactors, such as
nicotinamide adenine dinucleotide phosphate (NADP+). These cofactors are expensive to …

Redox reactions are essential to any currently known form of life and are at the core of a
majority of metabolic processes, such as cellular respiration or photosynthesis. As about …

Ene-reductases from the 'Old Yellow Enzyme'family of flavoproteins catalyze the asymmetric
reduction of various α, β-unsaturated compounds at the expense of a nicotinamide cofactor …