Progress in our understanding of several biological processes promises to broaden the
usefulness of Escherichia coli as a tool for gene expression. There is an expanding choice …

The purpose of this article is to provide a brief history of the development and application of
computer algorithms for the analysis and prediction of DNA binding sites. This problem can …

We have constructed a series of plasmid vectors (pBAD vectors) containing the PBAD
promoter of the araBAD (arabinose) operon and the gene encoding the positive and …

Plasmid expression vectors have been constructed that direct the synthesis of foreign
polypeptides in Escherichia coli as fusions with the C terminus of Sj26, a 26-kDa glutathione …

Covalent fusions between an mRNA and the peptide or protein that it encodes can be
generated by in vitro translation of synthetic mRNAs that carry puromycin, a peptidyl …

A guide to machine learning approaches and their application to the analysis of biological
data. An unprecedented wealth of data is being generated by genome sequencing projects …

The sequence of the 16,019 nucleotide-pair mitochondrial DNA (mtDNA) molecule of
Drosophila yakuba is presented. This molecule contains the genes for two rRNAs, 22 tRNAs …

We have developed a versatile Escherichia coli expression system based on the use of E.
coli thioredoxin (trxA) as a gene fusion partner. The broad utility of the system is illustrated …

Ribosome-mediated synthesis of proteins, us-ing messenger ribonucleic acid (mRNA) as
the template, is one of the hallmarks of earthly life forms. It is not surprising that the cellular …

Abstract The 16,775 base-pair mitochondrial genome of the white Leghorn chicken has
been cloned and sequenced. The avian genome encodes the same set of genes (13 …