Recent advances in self‐immobilizing fluorescent probes for in vivo imaging

Y Zhang, X Lv, Y Wang, X Chen, J Zhang… - Smart …, 2024 - Wiley Online Library
In situ precise detection of bioactive molecules with high sensitivity and spatiotemporal
resolution is essential for studying physiological events and disease diagnosis. The …

The strategy to improve the brightness of organic small-molecule fluorescent dyes for imaging

J Zhou, TB Ren, L Yuan - Chinese Chemical Letters, 2024 - Elsevier
Organic small molecule fluorophores have been widely used in biology and biochemistry to
study cellular structures and processes at high spatial and temporal resolution. Small …

Chemigenetic Far-Red Labels and Ca2+ Indicators Optimized for Photoacoustic Imaging

A Cook, N Kaydanov, B Ugarte-Uribe… - Journal of the …, 2024 - ACS Publications
Photoacoustic imaging is an emerging modality with significant promise for biomedical
applications such as neuroimaging, owing to its capability to capture large fields of view …

Utilization of chitosan nanocomposites loaded with quantum dots enables efficient and traceable DNA delivery

J He, P Hu, M Wang, G Qi, H Huang, D Zeng… - Colloids and Surfaces B …, 2025 - Elsevier
Chitosan is widely employed in gene carriers due to its excellent gene loading capacity,
ease of modification, and exceptional biodegradability. However, low gene delivery …

Emission Tuning of Nonconventional Luminescent Materials via Cluster Engineering

Y Wang, Z Liu, J Huang, H Wei, C Jiang, L Wei, B Jiang… - Small, 2025 - Wiley Online Library
Abstract Nonconventional Luminescent Materials (NLMs) with distinctive optical properties
are garnering significant attention. A key challenge in their practical application lies in …

Rationally Designed Cell Membrane Biomimetic Biosensing Platform for the Binding Analysis of Drugs with Intracellular Kinase Domain of Epidermal Growth Factor …

X Liu, Q Feng, Q Hu, M Li, L Jia, Y Zhao… - Analytical …, 2025 - ACS Publications
Biosensing technologies have demonstrated significant potential in exploring the binding of
drugs to receptor tyrosine kinases (RTKs). As a typical transmembrane receptor, there are …

Luminescent metal nanoclusters and their application in bioimaging

W Fei, SY Tang, MB Li - Nanoscale, 2024 - pubs.rsc.org
Owing to their unique optical properties and atomically precise structures, metal
nanoclusters (MNCs) constitute a new generation of optical probe materials. This mini …

Construction of a mitochondrial-targeting near-infrared fluorescent probe for detection of viscosity changes in type 2 diabetes mellitus and nonalcoholic steatohepatitis

X Ren, ZN Sayed, S Shi, J Hao, J Gao, J Wu, H Zhang… - Talanta, 2025 - Elsevier
The intracellular viscosity plays a pivotal role as a physicochemical factor and an important
indicator of organelles performance. Abnormal changes in subcellular viscosity are often …

Fluorescent probes for the visualization of membrane microdomain, deformation, and fusion

PH Tong, TY Wu, M Li, HB Wang, F Zheng… - Smart …, 2024 - Wiley Online Library
The cell membrane, a fluid interface composed of self‐assembled phospholipid molecules,
is a vital component of biological systems that maintains cellular stability and prevents the …

Naphthalimide-derived Fluorogenic SNAP Probe for Real-time Monitoring Protein Degradation

X Zhou, L Miao, Y Chen, J Shi, Q Qiao… - Chemical …, 2025 - pubs.rsc.org
We developed the fluorogenic SNAP probe BGAN-8C to monitor protein degradation. It
exhibited a 6-fold fluorescence enhancement upon binding with SNAP-tag. After the SNAP …