The potential of PIK3CA, KRAS, BRAF, and APC hotspot mutations as a non-invasive detection method for colorectal cancer
Background Early diagnosis of colorectal cancer (CRC) can lead to prompt treatment
modalities. Circulating cell-free DNA (cfDNA) analysis provides an alternative non-invasive …
modalities. Circulating cell-free DNA (cfDNA) analysis provides an alternative non-invasive …
Prediction of anticancer drug sensitivity using an interpretable model guided by deep learning
W Pang, M Chen, Y Qin - BMC bioinformatics, 2024 - Springer
Background The prediction of drug sensitivity plays a crucial role in improving the
therapeutic effect of drugs. However, testing the effectiveness of drugs is challenging due to …
therapeutic effect of drugs. However, testing the effectiveness of drugs is challenging due to …
Frequency of KRAS and BRAF mutations in colorectal carcinoma and their association with clinical-pathological characteristics in a tertiary hospital in Kenya
S Gakinya, A Njau, A Abdallah, A Nzioka… - Frontiers in …, 2024 - frontiersin.org
Introduction Colorectal carcinoma is a leading cause of cancer morbidity and mortality
globally. Its management includes the use of targeted therapy which require assessment for …
globally. Its management includes the use of targeted therapy which require assessment for …
RAS, BRAF, and MMR system mutations in metastatic colorectal cancers: an observational study
H Khoshnoudi, AY Joybari, PN Sanatdoost… - IJS …, 2024 - journals.lww.com
Methods: The present study is a descriptive cross-sectional study on patients with MCRCs
referred to a tertiary medical center in Iran from March 2015 to March 2022. Ethics approval …
referred to a tertiary medical center in Iran from March 2015 to March 2022. Ethics approval …
Anti-inflammatory and Apoptotic Effects of Levisticum Officinale Koch Extracts on HT 29 and Caco-2 Human Colorectal Carcinoma Cell Lines
Background: Colorectal cancer is among the deadliest cancers in the world. Due to the
occurrence of side effects related to current standard therapy, researchers are seeking better …
occurrence of side effects related to current standard therapy, researchers are seeking better …
Evaluation of correlation of miR-141 expression changes with common mutations of K-Ras gene and its relationship with prognosis in tumor tissue of colorectal cancer …
M Arkani, A Hesampour Mahallati… - Medical Science Journal …, 2023 - tmuj.iautmu.ac.ir
Background: In many human malignant tumors, the expression of micro RNA molecules is
dysfunctional. The purpose of this study was to investigate the miR-141 marker as a possible …
dysfunctional. The purpose of this study was to investigate the miR-141 marker as a possible …
[HTML][HTML] Evaluation of BRAF-V600E gene mutation in colon tissue of patients with colorectal cancer in Iran
K Farahani, B Poopak, M Ebadi… - Medical Science Journal …, 2022 - tmuj.iautmu.ac.ir
Background: Colorectal cancer is one of the most common types of cancer and the cause of
death of a large number of patients and requires investigating the causes of the disease and …
death of a large number of patients and requires investigating the causes of the disease and …