The role of miRNA molecules in the miscarriage process

WJ Omeljaniuk, P Laudański… - Biology of Reproduction, 2023 - academic.oup.com
The etiology and pathogenesis of miscarriage, which is the most common pregnancy
complication, have not been fully elucidated. There is a constant search for new screening …

Circulating extracellular vesicular microRNA signatures in early gestation show an association with subsequent clinical features of pre-eclampsia

S Ghosh, S Thamotharan, J Fong, MYY Lei… - Scientific Reports, 2024 - nature.com
In a prospective cohort of subjects who subsequently developed preeclampsia (PE, n= 14)
versus remaining healthy (NORM, n= 12), early gestation circulating extracellular vesicles …

Hsa_circ_0002348 regulates trophoblast proliferation and apoptosis through miR-126-3p/BAK1 axis in preeclampsia

J Zhou, Y Zhao, P An, H Zhao, X Li, Y **ong - Journal of Translational …, 2023 - Springer
Background Preeclampsia is a common pregnancy complication characterized by high
blood pressure and damage to organs. Abnormal placenta and vascular function can lead to …

[HTML][HTML] Epigenetic Biomarkers in Thrombophilia-Related Pregnancy Complications: Mechanisms, Diagnostic Potential, and Therapeutic Implications: A Narrative …

CR Bardan, I Ioniță, M Iordache… - International Journal of …, 2024 - mdpi.com
Pregnancy complications associated with thrombophilia represent significant risks for
maternal and fetal health, leading to adverse outcomes such as pre-eclampsia, recurrent …

Cleistocalyx nervosum var. paniala mitigates oxidative stress and inflammation induced by PM10 soluble extract in trophoblast cells via miR-146a-5p

W Chaiwangyen, O Khantamat, K Pintha… - Scientific Reports, 2024 - nature.com
Air pollution poses a significant global concern, notably impacting pregnancy outcomes
through mechanisms such as DNA damage, oxidative stress, inflammation, and altered …

HMOX1 Participates in Pre-Eclampsia by Regulating the Proliferation, Apoptosis, and Angiogenesis Modulation Potential of Mesenchymal Stem Cells via VEGF

J Shi, M Su - Biochemical Genetics, 2024 - Springer
Mesenchymal stem cells (MSCs) are involved in the pathogenesis of pre-eclampsia (PE).
Heme oxygenase (HMOX) protects against placental cytotoxic injuries associated with PE …

Growth restriction in preeclampsia: lessons from animal models

JH Mallette, BF Crudup, BT Alexander - Current opinion in physiology, 2023 - Elsevier
Preeclampsia remains a major health concern for mother and child. Yet, treatment options
remain limited to early delivery. Placental dysfunction in preeclampsia occurs in response to …

MiR-135b-5p targets ADAM12 to suppress invasion and accelerate trophoblast apoptosis in preeclampsia

B Sun, T Jiang, J Yong, J Peng, S Dong, Y Gu, X Ji… - Placenta, 2023 - Elsevier
Introduction Preeclampsia was a serious complication often leaded to adverse pregnancy
outcomes. Abnormal placental miR-135b-5p expression in preeclampsia was observed in …

MicroRNAs targeting peroxisome proliferator-activated receptor (PPAR) gene are differentially expressed in low birth weight placentae

D Sundrani, A Karkhanis, K Randhir, T Panchanadikar… - Placenta, 2023 - Elsevier
Introduction Peroxisome proliferator-activated receptors (PPARs) are activated by natural
ligands like fatty acids and influence placental angiogenesis and pregnancy outcome …

[HTML][HTML] Polymorphisms in MicroRNA Biogenesis Genes and the Risk of Preeclampsia in Jordan

SJ Makhlouf, OF Khabour… - Biomedical and …, 2024 - journals.lww.com
Background: Preeclampsia (PE) is a serious pregnancy condition with a complex etiology
involving both environmental and genetic factors. This study investigated the association …