[HTML][HTML] Outcome measures and biomarkers for clinical trials in hereditary spastic paraplegia: a sco** review

SF Siow, D Yeow, LI Rudaks, F Jia, G Wali, CM Sue… - Genes, 2023 - mdpi.com
Hereditary spastic paraplegia (HSP) is characterized by progressive lower limb spasticity.
There is no disease-modifying treatment currently available. Therefore, standardized …

Sensitivity of neuroimaging indicators in monitoring the effects of interferon gamma treatment in Friedreich's ataxia

M Vavla, F Arrigoni, N Toschi, D Peruzzo… - Frontiers in …, 2020 - frontiersin.org
The identification of efficient markers of disease progression and response to possibly
effective treatments is a key priority for slowly progressive, rare and neurodegenerative …

Brain magnetic spectroscopy imaging and hereditary spastic paraplegia: a focused systematic review on current landmarks and future perspectives

M Vavla, D Montanaro, S Pizzighello, F Frijia… - Frontiers in …, 2020 - frontiersin.org
Magnetic resonance spectroscopy (MRS) is a non-invasive neuroimaging technique used to
investigate in vivo brain metabolites. MRS could provide a sensitive tool for the study of …

Retinal ganglion cell and microvascular density loss in hereditary spastic paraplegia

GN Turski, CA Turski, M Grobe-Einsler… - Restorative …, 2024 - journals.sagepub.com
Background: Hereditary spastic paraplegia (HSP) is characterized by progressive
degeneration of distal axons in the long corticospinal tracts. Loss of retinal cells and …

The role of inflammation in hereditary spastic paraplegia type 11

M Hörner - 2024 - opus.bibliothek.uni-wuerzburg.de
Hereditary spastic paraplegias (HSPs) are genetically-determined, neurodegenerative
disorders characterized by progressive weakness and spasticity of the lower limbs. Spastic …

[HTML][HTML] Hereditary spastic paraplegia

A Datta - medlink.com
Hereditary spastic paraplegia (HSP) | MedLink Neurology Log In Sign Up for a Free Account
Clinical Categories Developmental Malformations Epilepsy & Seizures General Child Neurology …