Challenges and applications in generative AI for clinical tabular data in physiology

C Umesh, M Mahendra, S Bej, O Wolkenhauer… - … -European Journal of …, 2024 - Springer
Recent advancements in generative approaches in AI have opened up the prospect of
synthetic tabular clinical data generation. From filling in missing values in real-world data …

Synthetic data: Generate avatar data on demand

T Lebrun, L Béziaud, T Allard, A Boutet… - … Conference on Web …, 2024 - Springer
Anonymization is crucial for the sharing of personal data in a privacy-aware manner yet it is
a complex task that requires to set up a trade-off between the robustness of anonymization …

Synthetic data as external control arms in scarce single-arm clinical trials

S Elvatun, D Knoors, S Brant, C Jonasson… - PLOS Digital …, 2025 - journals.plos.org
An external control arm based on health registry data can serve as an alternative
comparator in single-arm drug development studies that lack a benchmark for comparison to …

Anonymize or synthesize? Privacy-preserving methods for heart failure score analytics

TI Johann, K Otte, F Prasser… - European Heart Journal …, 2025 - academic.oup.com
Aims Data availability remains a critical challenge in modern, data-driven medical research.
Due to the sensitive nature of patient health records, they are rightfully subject to stringent …

Position Paper: Building Trust in Synthetic Data for Clinical AI

KAR Babu, S Mulay, O Prabhu… - arxiv preprint arxiv …, 2025 - arxiv.org
Deep generative models and synthetic medical data have shown significant promise in
addressing key challenges in healthcare, such as privacy concerns, data bias, and the …

Implementation and Evaluation of Models for Synthetic Generation of Spectral Signals to Balance Metabolomic Data

M Martin Asiain, F Londono-Hoyos… - Proceedings of the 11th …, 2024 - dl.acm.org
Although the advance of Artificial Intelligence (AI) in medicine is significant, its potential
impact depends on access to quality data. A particular challenge is class imbalance in …

Health Data: Exploring Emerging Privacy Enhancing Mechanisms

T Lebrun - 2024 - hal.science
Health data represents a large volume of information, generated daily and sensitive by
nature. However, sharing this data is essential for advancing research and, ultimately …

[PDF][PDF] Synthetic data generation for research–enabler for privacy-enhancing health data sharing?

GAM de Reuver, SS Hinrichs-Krapels, JHFJ Oosterhoff - 2024 - repository.tudelft.nl
Sharing personal health data can boost scientific research, in terms of increased
comprehension of diseases, diagnostics, treatments, and predictive capabilities. But …

Legal and Regulatory Perspectives on Synthetic Data as an Anonymization Strategy

A Boudewijn, AF Ferraris - J. Pers. Data Prot. L., 2024 - HeinOnline
In an increasingly digital world, the protection of personal data is paramount for individuals,
organizations, and regulators. As data collection technologies evolve, so must methods for …

[PDF][PDF] Assessing the Evolution and Influence of Medical Open Databases on Biomedical Research and Healthcare Innovation: A 25-Year Perspective with a Focus on …

CHC Wang, DC Tarng, DM Niu, SH Chiou, CY Wu… - s3.ca-central-1.amazonaws.com
The integration of medical open databases with artificial intelligence (AI) technologies marks
a transformative era in biomedical research and healthcare innovation. Over the past 25 …