Bone and skeletal muscle are integrated organs and their coupling has been considered
mainly a mechanical one in which bone serves as attachment site to muscle while muscle …

Colorectal cancer (CRC) is one of the most common aggressive carcinoma types worldwide,
characterized by unfavorable curative effect and poor prognosis. Epidemiological data re …

The rates of obesity and diabetes are increasing worldwide, whereas the age of onset for
both obesity and diabetes are decreasing steadily. Obesity and diabetes are associated with …

Hepatocyte differentiation, proliferation, and apoptosis are affected by growth factors
produced in liver. Insulin-like growth factor 1 and 2 (IGF1 and IGF2) act in response to …

Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

In evolutionary terms, GH and intracellular STAT 5 signaling is a very old regulatory system.
Whereas insulin dominates periprandially, GH may be viewed as the primary anabolic …

This review focuses on the systemic complications of acromegaly. Mortality in this disease is
increased mostly because of cardiovascular and respiratory diseases, although currently …

This investigation compared the effect of high‐volume (VOL) versus high‐intensity (INT)
resistance training on stimulating changes in muscle size and strength in resistance‐trained …

Fish body growth is a trait of major importance for individual survival and reproduction. It has
implications in population, ecology, and evolution. Somatic growth is controlled by the …

IGF-1 is a growth-promoting polypeptide that is essential for normal growth and
development. In serum, the majority of the IGFs exist in a 150-kDa complex including the IGF …