Modern societies are experiencing an increasing trend of reduced sleep duration, with
nocturnal slee** time below the recommended ranges for health. Epidemiological and …

Sleep-immune interactions are well-known phenomena in everyday life and folk wisdom.
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …

The discovery of reciprocal connections between the central nervous system, sleep and the
immune system has shown that sleep enhances immune defences and that afferent signals …

From asthma and heart disease to diabetes and obesity, the human microbiome plays a role
in the pathogenesis of each chronic health condition plaguing today's society. Recent work …

Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …

Background Sleep disturbance is associated with inflammatory disease risk and all-cause
mortality. Here, we assess global evidence linking sleep disturbance, sleep duration, and …

Sleep disturbances including insomnia independently contribute to risk of inflammatory
disorders and major depressive disorder. This review and overview provides an integrated …

The development of alcohol use disorder (AUD) involves binge or heavy drinking to high
levels of intoxication that leads to compulsive intake, the loss of control in limiting intake, and …

Sleep has a critical role in promoting health. Research over the past decade has
documented that sleep disturbance has a powerful influence on the risk of infectious …

Daytime nap** is a common, heritable behavior, but its genetic basis and causal
relationship with cardiometabolic health remain unclear. Here, we perform a genome-wide …