Nanodiscs: Game changer nano-therapeutics and structural biology tools
In recent years, engineering biocompatible HDL nanodiscs has garnered a great interest
with wide applications for for both drug delivery and structural biology. In this review, we …
with wide applications for for both drug delivery and structural biology. In this review, we …
Hydrogel-based therapeutic angiogenesis: An alternative treatment strategy for critical limb ischemia
Z **ng, C Zhao, S Wu, C Zhang, H Liu, Y Fan - Biomaterials, 2021 - Elsevier
Critical limb ischemia (CLI) is the most severe clinical manifestation of peripheral arterial
disease (PAD), resulting in the total or partial loss of limb function. Although the conventional …
disease (PAD), resulting in the total or partial loss of limb function. Although the conventional …
Plaque macrophage‐targeting nanosystems with cooperative Co‐regulation of ROS and TRAF6 for stabilization of atherosclerotic plaques
Chronic inflammatory microenvironment is the predominant milieu that promotes the
progression of atherosclerosis (AS). However, targeted regulation of the chronic …
progression of atherosclerosis (AS). However, targeted regulation of the chronic …
Designing nanodiscs as versatile platforms for on-demand therapy
Q Mu, H Deng, X An, G Liu, C Liu - Nanoscale, 2024 - pubs.rsc.org
Nowadays, there has been an increasing utilization of nanomedicines for disease treatment.
Nanodiscs (NDs) have emerged as a novel platform technology that garners significant …
Nanodiscs (NDs) have emerged as a novel platform technology that garners significant …
Neuregulin-1/PI3K signaling effects on oligodendrocyte proliferation, remyelination and behaviors deficit in a male mouse model of ischemic stroke
MY Cui, YQ Fu, ZL Li, Y Zheng, Y Yu, C Zhang… - Experimental …, 2023 - Elsevier
In this study, we investigated the effect of neuregulin-1 (NRG1) on demyelination and
neurological function in an ischemic stroke model, and further explored its neuroprotective …
neurological function in an ischemic stroke model, and further explored its neuroprotective …
Single-component nanodiscs via the thermal folding of amphiphilic graft copolymers with the adjusted flexibility of the main chain
T Nishimura, Y Hatatani, M Ando, Y Sasaki… - Chemical …, 2022 - pubs.rsc.org
Nanodiscs have attracted considerable attention as structural scaffolds for membrane-
protein research and as biomaterials in eg drug-delivery systems. However, conventional …
protein research and as biomaterials in eg drug-delivery systems. However, conventional …
A surface‐tailoring method for rapid non‐thermosensitive cell‐sheet engineering via functional polymer coatings
Cell sheet engineering, a technique utilizing a monolayer cell sheet, has recently emerged
as a promising technology for scaffold‐free tissue engineering. In contrast to conventional …
as a promising technology for scaffold‐free tissue engineering. In contrast to conventional …
Synthetic High‐Density Lipoprotein‐Based Nanomedicine to Silence SOCS1 in Tumor Microenvironment and Trigger Antitumor Immunity against Glioma
C Yang, Y Li, Y Yang, Q Ni, Z Zhang… - Angewandte …, 2023 - Wiley Online Library
Immunotherapies have shed light on the treatment of many cancers, but have not improved
the outcomes of glioma (GBM). Here, we demonstrated that suppressor of cytokine signaling …
the outcomes of glioma (GBM). Here, we demonstrated that suppressor of cytokine signaling …
SP prevents T2DM complications by immunomodulation
SM Baek, K Kim, S Kim, Y Son, HS Hong, SY Yu - Scientific Reports, 2020 - nature.com
Type 2 diabetic mellitus (T2DM) is characterized by systemic inflammation and insulin
resistance due to obesity, and this leads to critical complications, including retinopathy and …
resistance due to obesity, and this leads to critical complications, including retinopathy and …
Pien Tze Huang accelerated wound healing by inhibition of abnormal fibroblast apoptosis in Streptozotocin induced diabetic mice
Y Yan, X Liu, Y Zhuang, Y Zhai, X Yang, Y Yang… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Diabetic foot ulcer is one of the most serious complications
of diabetes. Effective medical treatment regarding improvement of ulcer healing in patients is …
of diabetes. Effective medical treatment regarding improvement of ulcer healing in patients is …