Effects of mechanical stress stimulation on function and expression mechanism of osteoblasts

P Liu, J Tu, W Wang, Z Li, Y Li, X Yu… - … in Bioengineering and …, 2022 - frontiersin.org
Osteoclasts and osteoblasts play a major role in bone tissue homeostasis. The homeostasis
and integrity of bone tissue are maintained by ensuring a balance between osteoclastic and …

[HTML][HTML] Biophysical modulation of the mitochondrial metabolism and redox in bone homeostasis and osteoporosis: how biophysics converts into bioenergetics

FS Wang, RW Wu, YS Chen, JY Ko, H Jahr, WS Lian - Antioxidants, 2021 - mdpi.com
Bone-forming cells build mineralized microstructure and couple with bone-resorbing cells,
harmonizing bone mineral acquisition, and remodeling to maintain bone mass homeostasis …

Piezo1 regulates migration and invasion of breast cancer cells via modulating cell mechanobiological properties

Y Yu, X Wu, S Liu, H Zhao, B Li… - Acta Biochimica et …, 2021 - academic.oup.com
Cell migration and invasion are two essential processes during cancer metastasis.
Increasing evidence has shown that the Piezo1 channel is involved in mediating cell …

The lack of mass transfer in bone lacunar-canalicular system may be the decisive factor of osteoporosis under microgravity

H Wang, H Liu, X Wang, C Zhang - Life Sciences in Space Research, 2021 - Elsevier
Abstract During spaceflight, astronauts experience 1–1.5% bone loss per month, especially
in the lumbar spine, pelvis and lower limbs. The bone loss leads to osteoporosis and …

Dependency of deformation of cell nucleus on stretch direction of tissue: Relation to anisotropic response of aortic media to hypertension

Y Fan, J Wang, J Kim, E Maeda, T Matsumoto - Journal of the Mechanical …, 2022 - Elsevier
The deformation of the cell nucleus may cause dispersion of chromatin and eventually
enhance transcription, translation, and protein expression. If this happens in the …

[HTML][HTML] The effect of different gravity fields on mass transfer in the rat bone lacunar-canalicular system

H Wang, J Wang, K Li, L Gao, A Wang, S Wei… - Medicine in Novel …, 2023 - Elsevier
The bone lacunar-canalicular system (LCS) is an important microscopic infrastructure for
signaling and solute transport in bone tissue, which guarantees normal physiological …

生物力学作用对成骨细胞生物特性的影响

熊婉琦, **振豪, 崔焱, 刘家河, **陈致, 吴铭健… - **组织工程研究, 2024 - cjter.com
生物力学作用对成骨细胞生物特性的影响 Page 1 Chinese Journal of Tissue Engineering
Research|Vol 28|No.21|July 2024|3407 **组织工程研究 Chinese Journal of Tissue …

Some challenges in gravity related research

JJWA van Loon - Frontiers in Space Technologies, 2020 - frontiersin.org
Some Challenges in Gravity Related Research.'Microgravity'is not a science, as some
presume, but a particular environment where science can be performed. The main reason to …

Mechanisms for cells responding to mechanical stresses via the cell membrane

D Guo, Z Li, C Jiang, X Xu, D Shao… - BIBE 2019; The Third …, 2019 - ieeexplore.ieee.org
Cell membranes play an important role in various activities of cells. In particular, cell
membranes are involved in maintaining intracellular ion balance and activating ion …

Effects of biomechanics on biological characteristics of osteoblasts

W **ong, Z Li, Y Cui, J Liu, C Li, M Wu, Y Li… - Chinese Journal of …, 2024 - cjter.com
BACKGROUND: Bone formation is the process by which osteoblasts synthesize and secrete
osteoid and promote its mineralization, which generally involves mechanical signal …