The extracellular vesicle generation paradox: a bacterial point of view

HM McMillan, MJ Kuehn - The EMBO Journal, 2021 - embopress.org
All bacteria produce secreted vesicles that carry out a variety of important biological
functions. These extracellular vesicles can improve adaptation and survival by relieving …

Overcoming intrinsic and acquired resistance mechanisms associated with the cell wall of gram-negative bacteria

RE Impey, DA Hawkins, JM Sutton… - Antibiotics, 2020 - mdpi.com
The global increase in multi-drug-resistant bacteria is severely impacting our ability to
effectively treat common infections. For Gram-negative bacteria, their intrinsic and acquired …

Antibiotic resistance and regulation of the gram-negative bacterial outer membrane barrier by host innate immune molecules

SI Miller - MBio, 2016 - Am Soc Microbiol
The Gram-negative outer membrane is an important barrier that provides protection against
toxic compounds, which include antibiotics and host innate immune molecules such as …

Mastering the Gram-negative bacterial barrier–Chemical approaches to increase bacterial bioavailability of antibiotics

HK Ropponen, R Richter, AKH Hirsch… - Advanced Drug Delivery …, 2021 - Elsevier
To win the battle against resistant, pathogenic bacteria, novel classes of anti-infectives and
targets are urgently needed. Bacterial uptake, distribution, metabolic and efflux pathways of …

Luteolin exhibits antimicrobial actions against Salmonella Typhimurium and Escherichia coli: Impairment of cell adhesion, membrane integrity, and energy metabolism

AGMSU Mahamud, M Ashrafudoulla, S Nahar… - Food Control, 2024 - Elsevier
There has been an increasing interest in phytochemicals with antimicrobial properties in
food safety management. However, the mechanisms of action of phytochemicals remain …

Synergistic effects of benzyl isothiocyanate and resveratrol against Listeria monocytogenes and their application in chicken meat preservation

Z Li, H Wu, J Liu, H Hao, J Bi, H Hou, G Zhang - Food Chemistry, 2023 - Elsevier
This study aimed to investigate the synergistic effects of benzyl isothiocyanate (BITC) and
resveratrol (RS) on Listeria monocytogenes and their application in chicken meat …

Programmed Death of Injured Pseudomonas aeruginosa on Mechano-Bactericidal Surfaces

S Zhao, Z Li, DP Linklater, L Han, P **, L Wen… - Nano Letters, 2022 - ACS Publications
Mechano-bactericidal surfaces deliver lethal effects to contacting bacteria. Until now, cell
death has been attributed to the mechanical stress imparted to the bacterial cell envelope by …

Reversing resistance to counter antimicrobial resistance in the World Health Organisation's critical priority of most dangerous pathogens

H Venter - Bioscience reports, 2019 - portlandpress.com
The speed at which bacteria develop antimicrobial resistance far outpace drug discovery
and development efforts resulting in untreatable infections. The World Health Organisation …

Infection leaves a genetic and functional mark on the gut population of a commensal bacterium

C Tawk, B Lim, NA Bencivenga-Barry, HJ Lees… - Cell host & …, 2023 - cell.com
Gastrointestinal infection changes microbiome composition and gene expression. In this
study, we demonstrate that enteric infection also promotes rapid genetic adaptation in a gut …

Nutrient sensing and the oxidative stress response

H Luo, HH Chiang, M Louw, A Susanto… - Trends in Endocrinology & …, 2017 - cell.com
The simplicity and effectiveness of calorie restriction (CR) in lifespan and healthspan
extension have fascinated generations searching for the Fountain of Youth. CR reduces …