Traditional laboratory experiments, rehabilitation clinics, and wearable sensors offer
biomechanists a wealth of data on healthy and pathological movement. To harness the …

The muscles of the lower limb, particularly the quadriceps, play an important role in the
genesis and management of knee osteoarthritis (OA). At the knee, muscles function to …

Principal component analysis of a data matrix extracts the dominant patterns in the matrix in
terms of a complementary set of score and loading plots. It is the responsibility of the data …

OBJECTIVE: To respond to a pre-specified set of questions posed by the United States Food
and Drug Administration (FDA) on defining the disease state to inform the clinical …

BACKGROUND: Compared to matched controls, knee osteoarthritis patients walk with
altered, kinematics, kinetics and muscle activity. Studies of osteoarthritis patient gait have …

BACKGROUND: While knee osteoarthritis has been shown to affect a multitude of kinematic,
kinetic and temporo-spatial gait parameters, few investigations have examined the effect of …

Anterior knee pain is one of the most common causes of persistent problems after
implantation of a total knee replacement. It can occur in patients with or without patellar …

Background As knee osteoarthritis (OA) cannot be cured, treatments that slow structural
disease progression are a priority. Knee muscle activation has a potential role in OA …

Many biomedical, orthopaedic, and industrial applications are emerging that will benefit from
personalized neuromusculoskeletal models. Applications include refined diagnostics …

The muscles of the lower limb play an important role in the genesis and management of
knee osteoarthritis (OA). This article outlines the influence of muscle activity on knee joint …