Cancer diagnosis and treatment constitute profoundly stressful experiences involving
unique and common challenges that generate uncertainty, fear, and emotional distress …

Exposure to chronic adverse conditions, and the resultant activation of the neurobiological
response cascade, has been associated with an increased risk of early onset of age-related …

The range of psychosocial stress factors/processes (eg, chronic stress, distress states,
co**, social adversity) were reviewed as they relate to immune variables in cancer along …

Data from clinical and preclinical studies indicate that immune dysregulation, specifically of
inflammatory processes, is associated with symptoms of major depressive disorder (MDD) …

Sleep disturbances including insomnia independently contribute to risk of inflammatory
disorders and major depressive disorder. This review and overview provides an integrated …

Diagnostic criteria for mood disorders including major depressive disorder (MDD) largely
ignore biological factors in favor of behavioral symptoms. Compounding this paucity of …

We propose a model wherein chronic stress results in glucocorticoid receptor resistance
(GCR) that, in turn, results in failure to down-regulate inflammatory response. Here we test …

Across a variety of adverse life circumstances, such as social isolation and low
socioeconomic status, mammalian immune cells have been found to show a conserved …

Social stress is associated with altered immunity and higher incidence of anxiety-related
disorders. Repeated social defeat (RSD) is a murine stressor that primes peripheral myeloid …

Social stress can lead to the development of psychological problems ranging from
exaggerated anxiety and depression to antisocial and violence-related behaviors …