Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …

Polymer–drug conjugates have long been a mainstay of the drug delivery field, with several
conjugates successfully translated into clinical practice. The conjugation of therapeutic …

The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …

Formulating drugs into nanoparticles offers many attractive advantages over free drugs
including improved bioavailability, minimized toxic side effects, enhanced drug delivery …

Nanocarrier-based drug delivery systems hold impressive promise for biomedical
application because of their excellent water dispersibility, prolonged blood circulation time …

The considerable development of carrier-free nanodrugs has been achieved due to their
high drug-loading capability, simple preparation method, and offering “all-in-one” functional …

The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …

Drug molecules transformed into nanoparticles or endowed with nanostructures with or
without the aid of carrier materials are referred to as “nanomedicines” and can overcome …

Carrier-assistant drug delivery systems (DDSs) have been rapidly established for cancer
therapy and great strides have been made in recent years. However, further development of …

The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …