MicroRNA-mediated regulation of glucose and lipid metabolism

P Agbu, RW Carthew - Nature reviews Molecular cell biology, 2021 - nature.com
In animals, systemic control of metabolism is conducted by metabolic tissues and relies on
the regulated circulation of a plethora of molecules, such as hormones and lipoprotein …

The role of non-coding RNAs in oncology

FJ Slack, AM Chinnaiyan - Cell, 2019 - cell.com
For decades, research into cancer biology focused on the involvement of protein-coding
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …

miRBase: from microRNA sequences to function

A Kozomara, M Birgaoanu… - Nucleic acids …, 2019 - academic.oup.com
Abstract miRBase catalogs, names and distributes microRNA gene sequences. The latest
release of miRBase (v22) contains microRNA sequences from 271 organisms: 38 589 …

[HTML][HTML] Metazoan micrornas

DP Bartel - Cell, 2018 - cell.com
MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …

An estimate of the total number of true human miRNAs

J Alles, T Fehlmann, U Fischer, C Backes… - Nucleic acids …, 2019 - academic.oup.com
While the number of human miRNA candidates continuously increases, only a few of them
are completely characterized and experimentally validated. Toward determining the total …

Trends in the development of miRNA bioinformatics tools

L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …

[HTML][HTML] A network of noncoding regulatory RNAs acts in the mammalian brain

B Kleaveland, CY Shi, J Stefano, DP Bartel - Cell, 2018 - cell.com
Noncoding RNAs (ncRNAs) play increasingly appreciated gene-regulatory roles. Here, we
describe a regulatory network centered on four ncRNAs—a long ncRNA, a circular RNA …

An integrated expression atlas of miRNAs and their promoters in human and mouse

D De Rie, I Abugessaisa, T Alam, E Arner, P Arner… - Nature …, 2017 - nature.com
MicroRNAs (miRNAs) are short non-coding RNAs with key roles in cellular regulation. As
part of the fifth edition of the Functional Annotation of Mammalian Genome (FANTOM5) …

Revisiting criteria for plant microRNA annotation in the era of big data

MJ Axtell, BC Meyers - The Plant Cell, 2018 - academic.oup.com
Abstract MicroRNAs (miRNAs) are∼ 21-nucleotide-long regulatory RNAs that arise from
endonucleolytic processing of hairpin precursors. Many function as essential …

MirGeneDB 2.1: toward a complete sampling of all major animal phyla

B Fromm, E Høye, D Domanska, X Zhong… - Nucleic acids …, 2022 - academic.oup.com
We describe an update of MirGeneDB, the manually curated microRNA gene database.
Adhering to uniform and consistent criteria for microRNA annotation and nomenclature, we …