The discovery of vitamin E (α-tocopherol) began in 1922 as a vital component required in
reproduction. Today, there are eight naturally occurring vitamin E isoforms, namely α-, β-, γ …

Artemisinins are a family of sesquiterpene trioxane lactone anti-malarial agents originally
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …

Ferroptosis is a kind of regulated cell death, supporting the pathological process of lung
inflammation, including asthma. Quercetin (QCT), a kind of natural dietary flavonoid, exerts …

Asthma is defined as a chronic inflammatory disease of the airways; however, the underlying
physiological and immunological processes are not fully understood. Animal models have …

BACKGROUND: Nasal polyps (NPs) are characterized by eosinophilic inflammation, which
is generally considered sensitive to corticosteroid treatment. OBJECTIVES: We evaluated …

Leukotrienes (LTs) are lipid mediators that play pivotal roles in acute and chronic
inflammation and allergic diseases. They exert their biological effects by binding to specific …

Glucocorticoids (GCs) are steroidal ligands for the GC receptor (GR), which can function as
a ligand-activated transcription factor. These steroidal ligands and derivatives thereof are …

There is an unmet need in severe asthma where approximately 40% of patients exhibit poor
β-agonist responsiveness, suffer daily symptoms and show frequent exacerbations …

In this review, we highlight experiments conducted in our laboratories that have elucidated
functional roles for CD 4+ T‐helper type‐2 lymphocytes (TH 2 cells), their associated …

Asthma is a chronic inflammatory disease of the airways and there are no preventions or
cures. Inflammatory cells through the secretion of cytokines and pro‐inflammatory molecules …