Dietary (poly) phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases

D Del Rio, A Rodriguez-Mateos… - Antioxidants & redox …, 2013 - liebertpub.com
Human intervention trials have provided evidence for protective effects of various (poly)
phenol-rich foods against chronic disease, including cardiovascular disease …

Potential adverse effects of resveratrol: A literature review

A Shaito, AM Posadino, N Younes, H Hasan… - International journal of …, 2020 - mdpi.com
Due to its health benefits, resveratrol (RE) is one of the most researched natural
polyphenols. Resveratrol's health benefits were first highlighted in the early 1990s in the …

Therapeutic potential of resveratrol: the in vivo evidence

JA Baur, DA Sinclair - Nature reviews Drug discovery, 2006 - nature.com
Resveratrol, a constituent of red wine, has long been suspected to have cardioprotective
effects. Interest in this compound has been renewed in recent years, first from its …

Beneficial role of phytochemicals on oxidative stress and age‐related diseases

C Forni, F Facchiano, M Bartoli… - BioMed research …, 2019 - Wiley Online Library
Aging is related to a number of functional and morphological changes leading to
progressive decline of the biological functions of an organism. Reactive Oxygen Species …

Properties of Resveratrol: In Vitro and In Vivo Studies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans

J Gambini, M Inglés, G Olaso… - Oxidative medicine …, 2015 - Wiley Online Library
Plants containing resveratrol have been used effectively in traditional medicine for over
2000 years. It can be found in some plants, fruits, and derivatives, such as red wine …

Stimuli-responsive In situ gelling system for nose-to-brain drug delivery

M Agrawal, S Saraf, S Saraf, SK Dubey, A Puri… - Journal of Controlled …, 2020 - Elsevier
The diagnosis and treatment of neurological ailments always remain an utmost challenge for
research fraternity due to the presence of BBB. The intranasal route appeared as an …

Resveratrol and its human metabolites—effects on metabolic health and obesity

M Springer, S Moco - Nutrients, 2019 - mdpi.com
Resveratrol is one of the most widely studied polyphenols and it has been assigned a
plethora of metabolic effects with potential health benefits. Given its low bioavailability and …

Resveratrol and health–a comprehensive review of human clinical trials

JM Smoliga, JA Baur… - Molecular nutrition & food …, 2011 - Wiley Online Library
In the past decade, the small polyphenol resveratrol has received widespread attention as
either a potential therapy or as a preventive agent for numerous diseases. Studies using …

Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients

KR Patel, VA Brown, DJL Jones, RG Britton… - Cancer research, 2010 - AACR
Resveratrol is a phytochemical with chemopreventive activity in preclinical rodent models of
colorectal carcinogenesis. Antiproliferation is one of the many chemopreventive modes of …

Resveratrol and clinical trials: the crossroad from in vitro studies to human evidence

J Tomé-Carneiro, M Larrosa… - Current …, 2013 - benthamdirect.com
Resveratrol (3, 5, 4'-trihydroxy-trans-stilbene) is a non-flavonoid polyphenol that may be
present in a limited number of foodstuffs such as grapes and red wine. Resveratrol has been …