Development of organic semiconducting materials for deep-tissue optical imaging, phototherapy and photoactivation

J Li, K Pu - Chemical Society Reviews, 2019 - pubs.rsc.org
Biophotonics as a highly interdisciplinary frontier often requires the assistance of optical
agents to control the light pathways in cells, tissues and living organisms for specific …

Catalytic chemistry of glucose oxidase in cancer diagnosis and treatment

LH Fu, C Qi, J Lin, P Huang - Chemical Society Reviews, 2018 - pubs.rsc.org
Glucose oxidase (GOx) is an endogenous oxido-reductase that is widely distributed in living
organisms. Over recent years, GOx has attracted increasing interest in the biomedical field …

Recent advances on modulation of H2O2 in tumor microenvironment for enhanced cancer therapeutic efficacy

Z Chu, J Yang, W Zheng, J Sun, W Wang… - Coordination Chemistry …, 2023 - Elsevier
Due to the rapid proliferation of tumors, the hydrogen peroxide (H 2 O 2) concentration of
tumor cells is higher than that of normal cells, which can be used as an effective target for …

Glucose oxidase‐instructed multimodal synergistic cancer therapy

LH Fu, C Qi, YR Hu, J Lin, P Huang - Advanced Materials, 2019 - Wiley Online Library
Over the past 3 years, glucose oxidase (GOx) has aroused great research interest in the
context of cancer treatment due to its inherent biocompatibility and biodegradability, and its …

Cancer treatment through nanoparticle-facilitated fenton reaction

H Ranji-Burachaloo, PA Gurr, DE Dunstan, GG Qiao - ACS nano, 2018 - ACS Publications
Currently, cancer is the second largest cause of death worldwide and has reached critical
levels. In spite of all the efforts, common treatments including chemotherapy, photodynamic …

Two-Dimensional Metal–Organic Framework/Enzyme Hybrid Nanocatalyst as a Benign and Self-Activated Cascade Reagent for in Vivo Wound Healing

X Liu, Z Yan, Y Zhang, Z Liu, Y Sun, J Ren, X Qu - Acs Nano, 2019 - ACS Publications
Metal–organic frameworks (MOFs)-based peroxidase mimics have been seldom applied in
the biomedical field, especially in vivo. One of the main reasons is their optimum reactions …

Biodegradable manganese-doped calcium phosphate nanotheranostics for traceable cascade reaction-enhanced anti-tumor therapy

LH Fu, YR Hu, C Qi, T He, S Jiang, C Jiang, J He, J Qu… - Acs Nano, 2019 - ACS Publications
Glucose oxidase (GOx) has been recognized as a “star” enzyme catalyst involved in cancer
treatment in the past few years. Herein, GOx is mineralized with manganese-doped calcium …

Magnetic targeting, tumor microenvironment-responsive intelligent nanocatalysts for enhanced tumor ablation

L Feng, R **e, C Wang, S Gai, F He, D Yang, P Yang… - ACS …, 2018 - ACS Publications
Therapeutic nanosystems which can be triggered by the distinctive tumor microenvironment
possess great selectivity and safety to treat cancers via in situ transformation of nontoxic …

Enzyme‐mediated tumor starvation and phototherapy enhance mild‐temperature photothermal therapy

G Gao, YW Jiang, Y Guo, HR Jia… - Advanced Functional …, 2020 - Wiley Online Library
Compared with conventional tumor photothermal therapy (PTT), mild‐temperature PTT
brings less damage to normal tissues, but also tumor thermoresistance, introduced by the …

Nanozymes-engineered metal–organic frameworks for catalytic cascades-enhanced synergistic cancer therapy

C Liu, J **ng, OU Akakuru, L Luo, S Sun, R Zou… - Nano Letters, 2019 - ACS Publications
The efficiency of chemical intercommunication between enzymes in natural networks can be
significantly enhanced by the organized catalytic cascades. Nevertheless, the exploration of …