Mass spectrometry (MS) is one of the most widely used analytical techniques in many fields.
Recent developments in chemical and biological researches have drawn much attention to …

According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

The anion of pyridine, C5H5N−, has been thought to be short lived in the gas phase and
was only previously observed indirectly. In the condensed phase, C5H5N− is known to be …

ProLuCID, a new algorithm for peptide identification using tandem mass spectrometry and
protein sequence databases has been developed. This algorithm uses a three tier scoring …

We discuss the evolution of OrbitrapTM mass spectrometry (MS) from its birth in the late
1990s to its current role as one of the most prominent techniques for MS. The Orbitrap mass …

The rise of the “Top Down” method in the field of mass spectrometry-based proteomics has
ushered in a new age of promise and challenge for the characterization and identification of …

When non-mass spectrometrists are talking about mass spectrometry it rather often sounds
as if they were telling a story out of Poe's Tales of Mystery and Imagi-tion. Indeed, mass …

We describe the design and initial performance of the first 21 tesla Fourier transform ion
cyclotron resonance (FT-ICR) mass spectrometer. The 21 tesla magnet is the highest field …

Mass spectrometry (MS)–based high-throughput proteomics is the core technique for large-
scale protein characterization. Due to the extreme complexity of proteomes, sophisticated …

Although only a few years old, the combination of a linear ion trap with an Orbitrap analyzer
has become one of the standard mass spectrometers to characterize proteins and …