Diversity of molecular targets and signaling pathways for CBD

DL de Almeida, LA Devi - Pharmacology research & …, 2020 - Wiley Online Library
Cannabidiol (CBD) is the second most abundant component of the Cannabis plant and is
known to have effects distinct from Δ9‐tetrahydrocannabinol (THC). Many studies that …

Cannabidiol: State of the art and new challenges for therapeutic applications

S Pisanti, AM Malfitano, E Ciaglia, A Lamberti… - Pharmacology & …, 2017 - Elsevier
Over the past years, several lines of evidence support a therapeutic potential of Cannabis
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …

Scientific validation of cannabidiol for management of dog and cat diseases

I Corsato Alvarenga, KS Panickar… - Annual review of …, 2023 - annualreviews.org
Cannabidiol (CBD) is a non-psychotropic phytocannabinoid of the plant Cannabis sativa L.
CBD is increasingly being explored as an alternative to conventional therapies to treat …

Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …

EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology

A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

[HTML][HTML] Molecular targets of cannabidiol in neurological disorders

CI Bih, T Chen, AVW Nunn, M Bazelot, M Dallas… - …, 2015 - Elsevier
Cannabis has a long history of anecdotal medicinal use and limited licensed medicinal use.
Until recently, alleged clinical effects from anecdotal reports and the use of licensed …

Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

O Devinsky, MR Cilio, H Cross, J Fernandez‐Ruiz… - …, 2014 - Wiley Online Library
To present a summary of current scientific evidence about the cannabinoid, cannabidiol
(CBD) with regard to its relevance to epilepsy and other selected neuropsychiatric disorders …

[HTML][HTML] Cannabinoids in medicine: a multifaceted exploration of types, therapeutic applications, and emerging opportunities in neurodegenerative diseases and …

V Voicu, FM Brehar, C Toader, RA Covache-Busuioc… - Biomolecules, 2023 - mdpi.com
In this review article, we embark on a thorough exploration of cannabinoids, compounds that
have garnered considerable attention for their potential therapeutic applications. Initially, this …

Effects of cannabinoids and cannabinoid‐enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes

L De Petrocellis, A Ligresti, AS Moriello… - British journal of …, 2011 - Wiley Online Library
BACKGROUND AND PURPOSE Cannabidiol (CBD) and Δ9‐tetrahydrocannabinol (THC)
interact with transient receptor potential (TRP) channels and enzymes of the …

Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis …

EP Baron, P Lucas, J Eades, O Hogue - The journal of headache and pain, 2018 - Springer
Background Medicinal cannabis registries typically report pain as the most common reason
for use. It would be clinically useful to identify patterns of cannabis treatment in migraine and …