Evaluation of folate-functionalized nanoparticle drug delivery systems—Effectiveness and concerns

MAI Ibrahim, R Othman, CF Chee, F Ahmad Fisol - Biomedicines, 2023 - mdpi.com
Targeting folate receptors is a potential solution to low tumor selectivity concerning
conventional chemotherapeutics. Apart from antibody–drug conjugates, folate-functionalized …

Nanotechnology driven lipid and metalloid based formulations targeting blood–brain barrier (3B) for brain tumor

A **dal, Mainuddin, A Kumar, RK Ratnesh… - Indian Journal of …, 2024 - Springer
The evolution of nanotechnology-driven lipid and metalloid-based nanoformulations has
garnered significant attention for develo** effective drug delivery systems with …

Organotin (IV)‐Decorated Graphene Quantum Dots as Dual Platform for Molecular Imaging and Treatment of Triple Negative Breast Cancer

IJ Gómez, K Ovejero‐Paredes… - … A European Journal, 2023 - Wiley Online Library
The pharmacological activity of organotin (IV) complexes in cancer therapy is well
recognized but their large applicability is hampered by their poor water solubility. Hence …

Tin-loaded mesoporous silica nanoparticles: Antineoplastic properties and genotoxicity assessment

PC Choudante, SK Nethi, D Diaz-Garcia, S Prashar… - Biomaterials …, 2022 - Elsevier
Nanotechnology has immensely advanced the field of cancer diagnostics and treatment by
introducing potential delivery vehicles as carriers for drugs or therapeutic agents. In due …

Ru (II) polypyridine complex-functionalized mesoporous silica nanoparticles as photosensitizers for cancer targeted photodynamic therapy

J Karges, D Díaz-García, S Prashar… - ACS Applied Bio …, 2021 - ACS Publications
Cancer is the leading cause of death in the developed world. In the last few decades,
photodynamic therapy (PDT) has augmented the number of medical techniques to treat this …

New organotin (IV) complexes with a bis-acyl-hydrazone ligand: Synthesis, crystal structure and immobilization on magnetic mesoporous silica nanoparticles as a …

T Sedaghat, M Aminian, S Abaee, E Hoveizi… - Journal of Molecular …, 2023 - Elsevier
The new binuclear organotin (IV) complexes,(Me 2 Sn) 2 L (1) and (Ph 2 Sn) 2 L (2), have
been synthesized from reaction of R 2 SnCl 2 (R= Me or Ph) with bis (2-hydroxy-1 …

[HTML][HTML] Synthesis of a theranostic platform based on fibrous silica nanoparticles for the enhanced treatment of triple-negative breast cancer promoted by a …

K Ovejero-Paredes, D Díaz-García, I Mena-Palomo… - Biomaterials …, 2022 - Elsevier
A new series of theranostic silica materials based on fibrous silica particles acting as
nanocarriers of two different cytotoxic agents, namely, chlorambucil and an organotin …

Biological Use of Nanostructured Silica-Based Materials Functionalized with Metallodrugs: The Spanish Perspective

D Díaz-García, S Prashar, S Gómez-Ruiz - International Journal of …, 2023 - mdpi.com
Since the pioneering work of Vallet-Regí's group on the design and synthesis of
mesoporous silica-based materials with therapeutic applications, during the last 15 years …

[HTML][HTML] Study of cancer cell cytotoxicity, internalization and modulation of growth factors induced by transferrin-conjugated formulations of metallodrug-functionalized …

D Díaz-García, E Fischer-Fodor, CI Vlad… - Microporous and …, 2021 - Elsevier
Nano-sized materials have shown to have very high potential in anticancer therapy by an
adequate tuning of their functionalization and physico-chemical properties. This study is …

Synergistic effect of folate-conjugated polymers and 5-fluorouracil in the treatment of colon cancer

G Siemiaszko, K Niemirowicz-Laskowska… - Cancer …, 2021 - Springer
Background In recent years, targeted drug delivery strategies have received special
attention from the scientific world due to advantages such as more effective therapy and …