In light of pioneering findings in the 1980s and an estimation of more than 130 million global
annual births, umbilical cord blood (UCB) is considered to be the most plentiful reservoir of …

Foetal stem cells (FSCs) can be isolated during gestation from many different tissues such
as blood, liver and bone marrow as well as from a variety of extraembryonic tissues such as …

Mesenchymal stem cells (MSCs) have been investigated as promising candidates for use in
new cell-based therapeutic strategies such as mesenchyme-derived tissue repair. MSCs are …

Undesired immune responses have drastically hampered outcomes after allogeneic organ
transplantation and cell therapy, and also lead to inflammatory diseases and autoimmunity …

Major histocompatibility complex (MHC) molecules are key players in initiating immune
responses towards invading pathogens. Both MHC class I and class II genes are present in …

Severe perinatal asphyxia with hypoxic ischaemic encephalopathy occurs in approximately
1–2/1000 live births and is an important cause of cerebral palsy and associated neurological …

Mesenchymal stem cell (MSC) transplantation is regarded as a promising candidate for the
treatment of ischaemic heart disease. The major hurdles for successful clinical translation of …

Stem cell therapies are promising strategies to regenerate human injured tissues, including
ischemic myocardium. Here, we examined the acquisition of properties associated with …

Introduction: Various engineered 'cell-platforms' have been reported in recent years for the
possible treatment of myocardial infarction (MI) and end-stage heart failure. These …

For years, sufficient progress has been made in treating heart failure following myocardial
infarction; however, the social and economic burdens and the costs to world health systems …