Recent progress of nanostructure-based enrichment of circulating tumor cells and downstream analysis

L Guo, C Liu, M Qi, L Cheng, L Wang, C Li, B Dong - Lab on a Chip, 2023‏ - pubs.rsc.org
The isolation and detection of circulating tumor cells (CTCs) play an important role in early
cancer diagnosis and prognosis, providing easy access to identify metastatic cells before …

Rationally designed naringenin-conjugated polyester nanoparticles enable folate receptor-mediated peroral delivery of insulin

IM Heyns, R Ganugula, T Varma… - … Applied Materials & …, 2023‏ - ACS Publications
Receptor-mediated transcytosis of nanoparticles is paramount for the effective delivery of
various drugs. Here, we report the design and synthesis of highly functional nanoparticles …

Circulating tumor cells in solid malignancies: From advanced isolation technologies to biological understanding and clinical relevance in early diagnosis and …

D Janjua, A Chaudhary, U Joshi, T Tripathi… - Biochimica et Biophysica …, 2024‏ - Elsevier
Circulating tumor cells (CTCs) are shed from primary tumors and travel through the body via
circulation, eventually settling to form micrometastases under favorable conditions …

Targeted magnetochemotherapy modified by 5-Fu-loaded thermally on/off switching nanoheaters for the eradication of CT26 murine colon cancer by inducing …

S Shirvalilou, S Khoee, S Khoei, MR Karimi… - Cancer …, 2023‏ - Springer
Despite significant breakthroughs in diagnosis and treatment of colorectal cancer (CRC), the
extent of morbidity and mortality secondary to CRC is still concerning. In this study, we …

The secret lives of miniature batteries

S Toledo, S Mendel - Sensors, 2024‏ - mdpi.com
This article describes the design, implementation, and use of a new system to investigate the
behavior of small batteries that power sensor and wireless systems that consume relatively …

Role of Cell Adhesion in Cancer Metastasis Formation: A Review

D Burčík, J Macko, N Podrojková, J Demeterová… - ACS …, 2025‏ - ACS Publications
Intercellular adhesion is accompanied by several physical quantities and actions. In this
review, we tried to collect information about the influence of surface energy and its impact on …

Automation of 3D digital rolling circle amplification using a 3D-printed liquid handler

S Shin, HG Yun, H Chung, H Cho, S Choi - Biosensors and Bioelectronics, 2024‏ - Elsevier
Automation of liquid handling is indispensable to improve throughput and reproducibility in
biochemical assays. However, the incorporation of automated systems into laboratory …

Simple Binding and Dissociation of a Sialoglycoprotein Using Boronic Acid-Modified Functional Interfaces on Microparticles

Y Horiguchi, M Yasuura, H Ashiba, ZL Tan, T Fukuda - Sensors, 2024‏ - mdpi.com
An overexpression of sialic acid is an indicator of metastatic cancer, and selective detection
of sialic acid shows potential for cancer diagnosis. Boronic acid is a promising candidate for …

Enrichment and Separation Technology for evaluation of Circulating Tumor Cells

Y Zhang, B Wang, J Cai, Y Yang, C Tang, X Zheng… - Talanta, 2024‏ - Elsevier
Circulating tumor cells (CTCs), first described by Ashworth in 1869,[1] refer to tumor cells in
human peripheral blood that are shed from primary or metastatic tumors.[2],[3],[4] In the …

Transferrin receptor-based circulating tumor cell enrichment provides a snapshot of the molecular landscape of solid tumors and correlates with clinical outcomes

G Galletti, A Halima, A Gjyrezi, J Zhang, B Zimmerman… - medRxiv, 2024‏ - medrxiv.org
Circulating tumor cells (CTCs) captured from the bloodstream of patients with solid tumors
have the potential to accelerate precision oncology by providing insight into tumor biology …