Over the recent years, it has become apparent that a deeper understanding of cell‐to‐cell
and organ‐to‐organ communication is necessary to fully comprehend both homeostatic and …

The major histocompatibility complex (MHC) class I molecules present peptide antigens to
MHC class I‐restricted CD8+ T lymphocytes to elicit an effective immune response. The …

During macroautophagy, cytoplasmic constituents are engulfed by autophagosomes.
Lysosomes fuse with closed autophagosomes but not with unclosed intermediate structures …

Autophagy, a conserved eukaryotic intracellular catabolic pathway, maintains cell
homeostasis by lysosomal degradation of cytosolic material engulfed in double membrane …

Autophagy is a cellular degradation pathway where double-membrane autophagosomes
form de novo to engulf cytoplasmic material destined for lysosomal degradation. This …

The p53 family member TAp63α plays an important role in maintaining the genetic integrity
in oocytes. DNA damage, in particular DNA double strand breaks, lead to the transformation …

During macroautophagy, phagophores establish multiple membrane contact sites (MCSs)
with other organelles that are pivotal for proper phagophore assembly and growth. In S …

Selective autophagy receptors (SARs) are central to cellular homeostatic and organellar
recycling pathways. Over the last two decades, more than 30 SARs have been discovered …

The co‐chaperone BAG3 is a hub for a variety of cellular pathways via its multiple domains
and its interaction with chaperones of the HSP70 family or small HSPs. During aging and …

Introduction Endoplasmic reticulum aminopeptidases 1 (ERAP1) and 2 (ERAP2) modulate a
plethora of physiological processes for the maintenance of homeostasis in different cellular …