[HTML][HTML] An evaluation on potential anti-oxidant and anti-inflammatory effects of Crocin

S Bastani, V Vahedian, M Rashidi, A Mir… - Biomedicine & …, 2022 - Elsevier
Crocin, an active ingredient derived from saffron, is one of the herbal components that has
recently been considered by researchers. Crocin has been shown to have many anti …

Comprehensive overview of Nrf2-related epigenetic regulations involved in ischemia-reperfusion injury

J Zhang, W Pan, Y Zhang, M Tan, Y Yin, Y Li… - …, 2022 - pmc.ncbi.nlm.nih.gov
Ischemic disease is a class of diseases in which an organ is ischemic due to vascular
occlusion, a major contributor to death and disability worldwide. However, when the blood …

Crocin molecular signaling pathways at a glance: A comprehensive review

M Boozari, H Hosseinzadeh - Phytotherapy Research, 2022 - Wiley Online Library
Crocin is a hydrophilic carotenoid that is synthesized in the flowers of the Crocus genus.
Numerous in vitro and in vivo research projects have been published about the biological …

Novel targets and therapeutic strategies to protect against hepatic ischemia reperfusion injury

X Mao, Y Cai, Y Chen, Y Wang, X Jiang, L Ye… - Frontiers in …, 2022 - frontiersin.org
Hepatic ischemia reperfusion injury (IRI), a fascinating topic that has drawn a lot of interest in
the last few years, is a major complication caused by a variety of clinical situations, such as …

Protective effect of crocin on BPA-induced liver toxicity in rats through inhibition of oxidative stress and downregulation of MAPK and MAPKAP signaling pathway and …

FV Hassani, S Mehri, K Abnous… - Food and Chemical …, 2017 - Elsevier
Bisphenol A (BPA) is an artificial environmental endocrine disrupting chemical and
commonly used as a monomer of polycarbonate plastics and epoxy resins. The aim of the …

Crocin alleviates myocardial ischemia/reperfusion-induced endoplasmic reticulum stress via regulation of miR-34a/Sirt1/Nrf2 pathway

X Wang, B Yuan, B Cheng, Y Liu, B Zhang, X Wang… - Shock, 2019 - journals.lww.com
Endoplasmic reticulum (ER) stress is associated with ischemia/reperfusion (I/R)-induced
cardiomyocyte apoptosis. Crocin could protect myocardial cells against I/R injury and …

[HTML][HTML] Antioxidant effect of p-coumaric acid on interleukin 1-β and tumor necrosis factor-α in rats with renal ischemic reperfusion

SM Godarzi, AV Gorji, B Gholizadeh, SA Mard… - Nefrologia, 2020 - Elsevier
Background and aims Renal ischemia-reperfusion occurs in some clinical conditions such
as kidney surgery that can leads to acute renal failure. The aim of this study was to …

Crocins: A comprehensive review of structural characteristics, pharmacokinetics and therapeutic effects

Y Song, Y Wang, Y Zheng, T Liu, C Zhang - Fitoterapia, 2021 - Elsevier
Crocins, as a kind of water-soluble carotenoid pigment, are a series of ester compounds
formed from crocetin and gentibiose or glucose, and mainly distributed among Crocus …

Role of crocin in several cancer cell lines: An updated review

A Veisi, G Akbari, SA Mard, G Badfar… - Iranian journal of …, 2020 - pmc.ncbi.nlm.nih.gov
Cancer is a major public health problem worldwide. The most important considerable
features of cancer cells are uncontrolled proliferation, up-regulated differentiation, and …

Role of zinc supplementation on ischemia/reperfusion injury in various organs

G Akbari - Biological Trace Element Research, 2020 - Springer
Abstract Ischemia-reperfusion (I/R) injury is a serious condition which is associated with
myocardial infarction, stroke, acute kidney injury, trauma, circulatory arrest, sickle cell …