Indole-based melatonin analogues: Synthetic approaches and biological activity

SY Wang, XC Shi, P Laborda - European Journal of Medicinal Chemistry, 2020 - Elsevier
Melatonin is a natural hormone primarily released by the pineal gland that regulates the
sleep-wake cycles. The diverse biological applications of melatonin, together with the need …

Pyrazolo[1,5-a]pyridine: Recent synthetic view on crucial heterocycles

D Devi Priya, M Nandhakumar… - Synthetic …, 2020 - Taylor & Francis
Abstract Pyrazolo [1, 5-a] pyridine is one of the important core of nitrogen ring junction
heterocyclic compounds. Due to novel and uncomplicated methods, ring junction motifs …

Scalable Sonochemical Synthetic Strategy for Pyrazolo[1,5-a]pyridine Derivatives: First Catalyst-Free Concerted [3 + 2] Cycloaddition of Alkyne and Alkene Derivatives to 2 …

HM Ibrahim, H Behbehani, NS Mostafa - ACS omega, 2019 - ACS Publications
A highly efficient and convenient one-pot sonochemical synthetic strategy has been
sophisticated for synthesizing a novel class of polysubstituted pyrazolo [1, 5-a] pyridines via …

Substrate selective synthesis of pyrazolo [1, 5-a] pyridines through [3+ 2] cycloaddition of N-aminopyridines and β-nitro styrenes

C Ravi, DC Mohan, NNK Reddy, S Adimurthy - RSC Advances, 2015 - pubs.rsc.org
Substrate selective synthesis of pyrazolo[1,5- a ]pyridines through [3 + 2] cycloaddition of N -aminopyridines
and β-nitro styrenes - RSC Advances (RSC Publishing) DOI:10.1039/C5RA06707C Royal …

Synthetic Strategy for Pyrazolo[1,5-a]pyridine and Pyrido[1,2-b]indazole Derivatives through AcOH and O2-Promoted Cross-dehydrogenative Coupling Reactions between 1,3 …

H Behbehani, HM Ibrahim - ACS omega, 2019 - ACS Publications
An efficient method has been developed for the synthesis of uniquely substituted pyrazolo
[1, 5-a] pyridine and pyrido [1, 2-b] indazole derivatives, which involves acetic acid and …

Copper-mediated synthesis of pyrazolo [1, 5-a] pyridines through oxidative linkage of C–C/N–N bonds

DC Mohan, C Ravi, SN Rao… - Organic & Biomolecular …, 2015 - pubs.rsc.org
Copper-mediated synthesis of pyrazolo [1, 5-a] pyridine-3-carboxylates through oxidative
linkage of C–C and N–N bonds under mild reaction conditions is described. This protocol is …

[3+ 2] Cycloaddition of N-Aminopyridines and Perfluoroalkynylphosphonates: Facile Synthesis of Perfluoroalkylated Pyrazolo [1, 5-a] pyridines Containing a …

Q Huang, D He, J Han, J Chen, W He, H Deng… - …, 2018 - thieme-connect.com
1, 3-Zwitterions generated from N-aminopyridines in the presence of base are trapped by
perfluoroalkynylphosphonates to yield a variety of perfluoroalkylated pyrazolo [1, 5-a] …

Development of Structurally Diverse N‐Heterocyclic Carbene Ligands via Palladium‐Copper‐Catalyzed Decarboxylative Arylation of Pyrazolo[1,5‐a]pyridine‐3 …

K Alam, SM Kim, DJ Kim, JK Park - Advanced Synthesis & …, 2016 - Wiley Online Library
A series of fused non‐classical normal N‐heterocyclic carbenes, Pyrpy‐NHC precursors
derived from pyrazolo [1, 5‐a] pyridines, has been prepared using palladium‐copper …

Direct access to 2-aminopyrazolo [1, 5-a] pyridines via N-amination/cyclization reactions of 2-pyridineacetonitriles

Y Nishigaya, K Umei, E Yamamoto, Y Kohno, S Seto - Tetrahedron Letters, 2014 - Elsevier
We describe the straightforward synthesis of 6-substituted-2-aminopyrazolo [1, 5-a]
pyridines from 2-pyridineacetonitriles by N-amination with O-(mesitylsulfonyl) hydroxylamine …

Palladium‐Catalyzed Direct Arylations of 1,2‐Azolo[1,5‐a]pyridines using Copper(I) Chloride as a Lewis Acid Activator and the Synthesis of 2,6‐Disubstituted …

KH Oh, SM Kim, MJ Lee, JK Park - Advanced Synthesis & …, 2015 - Wiley Online Library
A direct method for the arylation of 1, 2‐azolo [1, 5‐a] pyridines has been developed. In the
process, the fused pyridines react with aryl halides in the presence of the palladium complex …