[HTML][HTML] Therapeutic peptides: Historical perspectives, current development trends, and future directions
JL Lau, MK Dunn - Bioorganic & medicinal chemistry, 2018 - Elsevier
Peptide therapeutics have played a notable role in medical practice since the advent of
insulin therapy in the 1920s. Over 60 peptide drugs are approved in the United States and …
insulin therapy in the 1920s. Over 60 peptide drugs are approved in the United States and …
[HTML][HTML] Forty years of IVF
This monograph, written by the pioneers of IVF and reproductive medicine, celebrates the
history, achievements, and medical advancements made over the last 40 years in this …
history, achievements, and medical advancements made over the last 40 years in this …
Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders
BACKGROUND Kisspeptin is a key regulator of hypothalamic gonadotropin-releasing
hormone (GnRH) neurons and is essential for reproductive health. A specific kisspeptin …
hormone (GnRH) neurons and is essential for reproductive health. A specific kisspeptin …
Interventions to prevent or reduce the incidence and severity of ovarian hyperstimulation syndrome: a systematic umbrella review of the best clinical evidence
Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threating iatrogenic
complication of the early luteal phase and/or early pregnancy after in vitro fertilization (IVF) …
complication of the early luteal phase and/or early pregnancy after in vitro fertilization (IVF) …
Ovarian hyperstimulation syndrome: review and new classification criteria for reporting in clinical trials
STUDY QUESTION What is an objective approach that employs measurable and
reproducible physiologic changes as the basis for the classification of ovarian …
reproducible physiologic changes as the basis for the classification of ovarian …
Kisspeptin/GPR54 system: what do we know about its role in human reproduction?
Kisspeptin is involved in the control of human reproduction bridging the gap between the
sex steroid levels and feedback mechanisms that control the gonadotropin releasing …
sex steroid levels and feedback mechanisms that control the gonadotropin releasing …
Neuroendocrine determinants of polycystic ovary syndrome
A Szeliga, E Rudnicka, M Maciejewska-Jeske… - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women and a
major cause of anovulatory infertility. A diagnosis of PCOS is established based the …
major cause of anovulatory infertility. A diagnosis of PCOS is established based the …
Kisspeptin/kisspeptin receptor system in the ovary
Kisspeptins are a family of neuropeptides that are critical for initiating puberty and regulating
ovulation in sexually mature females via the central control of the hypothalamic–pituitary …
ovulation in sexually mature females via the central control of the hypothalamic–pituitary …
The emerging therapeutic potential of kisspeptin and neurokinin B
B Patel, K Koysombat, EG Mills, J Tsoutsouki… - Endocrine …, 2024 - academic.oup.com
Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …
Novel Concepts for Inducing Final Oocyte Maturation in In Vitro Fertilization Treatment
Infertility affects one in six of the population and increasingly couples require treatment with
assisted reproductive techniques. In vitro fertilization (IVF) treatment is most commonly …
assisted reproductive techniques. In vitro fertilization (IVF) treatment is most commonly …